PPP6C
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Official Full Name
protein phosphatase 6, catalytic subunit -
Overview
This gene encodes the catalytic subunit of protein phosphatase, a component of a signaling pathway regulating cell cycle progression. -
Synonyms
PPP6C;protein phosphatase 6, catalytic subunit;serine/threonine-protein phosphatase 6 catalytic subunit;PP6;serine/threonine protein phosphatase catalytic subunit;PP6C;FLJ92648;MGC12249
Recombinant Proteins
- Human
- Zebrafish
- Mouse
- Chicken
- Rat
- E.coli
- Mammalian Cells
- Wheat Germ
- In Vitro Cell Free System
- HEK293
- His
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| PPP6C-1928H | Recombinant Human PPP6C, His-tagged | E.coli | Human | His | 1-305aa | |
| PPP6C-11238Z | Recombinant Zebrafish PPP6C | Mammalian Cells | Zebrafish | His |
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| PPP6C-13276M | Recombinant Mouse PPP6C Protein | Mammalian Cells | Mouse | His |
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| PPP6C-29541TH | Recombinant Human PPP6C | Wheat Germ | Human | Non | 305 amino acids |
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| PPP6C-3597C | Recombinant Chicken PPP6C | Mammalian Cells | Chicken | His |
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| PPP6C-4646R | Recombinant Rat PPP6C Protein | Mammalian Cells | Rat | His |
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| PPP6C-1407HCL | Recombinant Human PPP6C cell lysate | Human | Non |
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| PPP6C-400HF | Recombinant Full Length Human PPP6C Protein | In Vitro Cell Free System | Human | Full L. 305 amino acids |
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| PPP6C-4305R | Recombinant Rat PPP6C Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| PPP6C-4305R-B | Recombinant Rat PPP6C Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| PPP6C-7046M | Recombinant Mouse PPP6C Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| PPP6C-7046M-B | Recombinant Mouse PPP6C Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
PPP6C involved in several pathways and played different roles in them. We selected most pathways PPP6C participated on our site, such as Asparagine N-linked glycosylation,COPII (Coat Protein 2) Mediated Vesicle Transport,ER to Golgi Anterograde Transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with PPP6C were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolism of proteins | NOP56,ADAMTS20,TBCD,IGFBP5,NAPG,THSD7A,ARSI,DPP4,ADAMTSL1,GNE |
| Vesicle-mediated transport | CX27.5,TRAPPC10,TPD52L1,CX30.3,AP4B1,RALAA,SNF8,HIP1RB,TRAPPC5,PLDN |
| Asparagine N-linked glycosylation | DDOST,USO1,ST6GAL2B,PREB,SLC35A1,NEU4,MAN1A2,CSNK1D,TRAPPC1,TRAPPC3 |
| COPII (Coat Protein 2) Mediated Vesicle Transport | TRAPPC6B,NAPG,USO1,CTSZ,NAPAA,LMAN2L,TRAPPC9,SEC23IP,PREB,SCFD1 |
| ER to Golgi Anterograde Transport | TRAPPC6BL,MIA3,CNIH,NSFA,BET1,NAPG,TRAPPC10,TRAPPC6B,PPP6R3,CTAGE5 |
| Membrane Trafficking | CPD,TFR1B,FTH1A,SNX9A,RALAA,GJB7,GJD3,FTH1B,MIA3,CLVS2 |
| Post-translational protein modification | UBA2,WDR85,ADAMTS13,SMC5,THSD1,DNAJC24,DPH2,EIF5A,PIGK,NEU4 |
| Transport to the Golgi and subsequent modification | ANKRD28,SEC22C,SEC16B,TRAPPC6B,TRAPPC6A,PPP6R3,MGAT4B,TMED10,TRAPPC2L,SEC22A |
Protein Function
PPP6C has several biochemical functions, for example, metal ion binding,protein binding,protein serine/threonine phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PPP6C itself. We selected most functions PPP6C had, and list some proteins which have the same functions with PPP6C. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| metal ion binding | ZNF573,ZNF133,ADCY7,ZNF222,GTF3AA,ZNF76,ZNF480,SDHC,CNBPA,AMY1A |
| protein binding | HIST1H3H,PTGDR,ARPC3,CEACAM1,RAB6B,PLG,PRKCQ,PDCL,KRT79,ARHGEF40 |
| protein serine/threonine phosphatase activity | CDC14B,CTDNEP1B,PPM1DA,PPM1LA,PPP1R3D,PPM1A,PPP4C,PPM1LB,PPP1R3C,MTMR3 |
Interacting Protein
PPP6C has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PPP6C here. Most of them are supplied by our site. Hope this information will be useful for your research of PPP6C.
IGBP1;PPP6R1
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References
- Liu, Y; Zhang, LW; et al. DNA-PKcs Deficiency Inhibits Glioblastoma Cell-Derived Angiogenesis After Ionizing Radiation. JOURNAL OF CELLULAR PHYSIOLOGY 230:1094-1103(2015).
- Crajoinas, RO; Pessoa, TD; et al. Changes in the activity and expression of protein phosphatase-1 accompany the differential regulation of NHE3 before and after the onset of hypertension in spontaneously hypertensive rats. ACTA PHYSIOLOGICA 211:395-408(2014).
