PPP3R2
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Official Full Name
protein phosphatase 3, regulatory subunit B, beta -
Overview
Calcineurin subunit B type 2 is a protein that in humans is encoded by the PPP3R2 gene. -
Synonyms
PPP3R2;protein phosphatase 3, regulatory subunit B, beta;calcineurin subunit B type 2;calcineurin B;type II (19kDa);PPP3RL;protein phosphatase 2B regulatory subunit 2;protein phosphatase 3;regulatory subunit B (calcineurin B) like;Calcineurin B like protein;Calcineurin B type II (19kDa);Calcineurin B type II;Calcineurin B-like protein;Calcineurin BII;Calcineurin subunit B isoform 2;CANB2_HUMAN;CBLP;CBLP like;CNBII;PPP3R1-like;Protein phosphatase 3 (formerly 2B) regulatory subunit B (19kD) beta isoform (calcineurin B type II);Protein phosphatase 3 (formerly 2B) regulatory subunit B beta isoform;Protein phosphatase 3 regulatory subunit B (19kD) beta isoform (calcineurin B type II);Protein phosphatase 3 regulatory subunit B (calcineurin B) like;Protein phosphatase 3 regulatory subunit B beta;Protein phosphatase 3 regulatory subunit B beta isoform;OTTHUMP00000021813;calcineurin B, type II (19kDa)
Recombinant Proteins
- Human
- Rat
- Mouse
- E.coli
- Mammalian Cells
- HEK293
- GST
- His
- Non
- DDK
- Myc
- Avi
- Fc
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| PPP3R2-1924H | Recombinant Human PPP3R2, GST-tagged | E.coli | Human | GST | 1-173aa | |
| PPP3R2-29542TH | Recombinant Human PPP3R2, His-tagged | E.coli | Human | His | 173 amino acids |
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| PPP3R2-4642R | Recombinant Rat PPP3R2 Protein | Mammalian Cells | Rat | His |
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| PPP3R2-973H | Recombinant Human Protein Phosphatase 3, Regulatory Subunit B, His-tagged | E.coli | Human | His |
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| PPP3R2-2912HCL | Recombinant Human PPP3R2 293 Cell Lysate | HEK293 | Human | Non |
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| PPP3R2-1848H | Recombinant Human PPP3R2 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293 | Human | DDK&Myc |
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| Ppp3r2-1974M | Recombinant Mouse Ppp3r2 Protein, His-tagged | E.coli | Mouse | His | Met1-Val168 |
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| PPP3R2-4301R | Recombinant Rat PPP3R2 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | Avi&Fc&His |
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| PPP3R2-4301R-B | Recombinant Rat PPP3R2 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| PPP3R2-4745H | Recombinant Human PPP3R2 protein, GST-tagged | E.coli | Human | GST | 1-170aa |
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| Ppp3r2-5083M | Recombinant Mouse Ppp3r2 Protein, Myc/DDK-tagged | HEK293 | Mouse | DDK&Myc |
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Involved Pathway
PPP3R2 involved in several pathways and played different roles in them. We selected most pathways PPP3R2 participated on our site, such as MAPK signaling pathway,Calcium signaling pathway,cGMP-PKG signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PPP3R2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Glutamatergic synapse | GRM6,PLCB4,GRIA2,SLC1A3,SLC38A1,GRM2,PRKACG,SLC38A3,PPP3R1,DLGAP1 |
| Osteoclast differentiation | TNFRSF11A,PPP3CC,MAP2K6,TYROBP,FHL2,STAT2,MAPK8,LILRB4,LILRB5,LILRB1 |
| Apoptosis | PRKAR2B,CAPN2B,DBNL,DNM1L,IL3,BIDA,DSP,PIK3CG,PLEC,PRKACB |
| Wnt signaling pathway | PRICKLE1A,FZD8A,PRKACB,TLE3A,WNT6,FZD7,WNT2BB,MMP7,LEF1,PRKCG |
| HTLV-I infection | WNT5B,ANAPC4,NFKB1,HLA-A,SRF,HRAS,IL15RA,KRAS,TNF,IL2RB |
| Renin secretion | PPP3CC,AGTR1B,CALM3,PPP3CA,PLCB2,ORAI1,REN,PTGER2,PTGER4,GUCY1B3 |
| B Cell Receptor Signaling Pathway | PIK3AP1,GSK3B,ACTR2,ARPC2,PTPN18,PPP3CC,PIK3CD,INPPL1,BLNK,BTK |
| Alzheimers disease | ATP5O,NOS1,FAS,UQCRC1,ATP5G3,NDUFS8,NDUFA1,CALM3,MAPT,NDUFB9 |
| MAPK signaling pathway | GNG12A,NLK1,KRAS,BRAF,RELB,GNA12,FGF4,MAP4K3,DUSP3,HSPB1 |
Protein Function
PPP3R2 has several biochemical functions, for example, calcium ion binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PPP3R2 itself. We selected most functions PPP3R2 had, and list some proteins which have the same functions with PPP3R2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| calcium ion binding | HPCA,PTBP3,CDK5R1,PLCD1B,CALM1,AP1S2,C1R,BMP1,PCDH10B,CRELD2 |
| protein binding | MED31,NOA1,VAMP1,HSF1,GRIP1,THOC7,LDB3,FBXO3,CELF1,DUT |
Interacting Protein
PPP3R2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PPP3R2 here. Most of them are supplied by our site. Hope this information will be useful for your research of PPP3R2.
TFCP2;AURKA;BUB1;CD14;CCND1;APC;MSH2;PTPN12;PTPRJ;SMAD4;PDGFRL;FBXW7;DLC1;MLH3
Resources
Research Area
Calcium-binding Proteins and Related MoleculesPhosphatases in the Akt Pathway
Wnt Intracellular Signaling
C-type Lectin Receptors
Related Services
Related Products
References
- Fleming, I; Busse, R; et al. Tyrosine phosphorylation and bradykinin-induced signaling in endothelial cells. AMERICAN JOURNAL OF CARDIOLOGY 80:A102-A109(1997).
- Csortos, C; Zolnierowicz, S; et al. High complexity in the expression of the B' subunit of protein phosphatase 2A(0) - Evidence for the existence of at least seven novel isoforms. JOURNAL OF BIOLOGICAL CHEMISTRY 271:2578-2588(1996).
