PPP1R3A
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Official Full Name
protein phosphatase 1, regulatory subunit 3A -
Overview
The glycogen-associated form of protein phosphatase-1 (PP1) derived from skeletal muscle is a heterodimer composed of a 37-kD catalytic subunit and a 124-kD targeting and regulatory subunit. This gene encodes the regulatory subunit which binds to muscle glycogen with high affinity, thereby enhancing dephosphorylation of glycogen-bound substrates for PP1 such as glycogen synthase and glycogen phosphorylase kinase. -
Synonyms
PPP1R3A;protein phosphatase 1, regulatory subunit 3A;PPP1R3, protein phosphatase 1, regulatory (inhibitor) subunit 3A , protein phosphatase 1, regulatory (inhibitor) subunit 3A (glycogen and sarcoplasmic reticulum binding subunit, skeletal muscle);protein phosphatase 1 regulatory subunit 3A;glycogen associated regulatory subunit of protein phosphatase 1;GM;protein phosphatase 1 regulatory subunit GM;PPP1R3;protein phosphatase 1, regulatory (inhibitor) subunit 3A;Glycogen and sarcoplasmic reticulum binding subunit, skeletal muscle;PP1G;PPR3A_HUMAN;Protein phosphatase 1 glycogen-associated regulatory subunit;Protein phosphatase type-1 glycogen targeting subunit;RG1;Serine /threonine specific protein phosphatase;Type 1 protein phosphatase skeletal muscle glycogen targeting subunit;protein phosphatase 1 glycogen- associated regulatory subunit;glycogen-associated regulatory subunit of protein phosphatase-1;type-1 protein phosphatase skeletal muscle glycogen targeting subunit
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| PPP1R3A-13237M | Recombinant Mouse PPP1R3A Protein | Mammalian Cells | Mouse | His |
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| PPP1R3A-31051TH | Recombinant Human PPP1R3A | Wheat Germ | Human | Non | 99 amino acids |
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| PPP1R3A-2936HCL | Recombinant Human PPP1R3A 293 Cell Lysate | HEK293 | Human | Non |
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| Ppp1r3a-1968R | Recombinant Rat Ppp1r3a Protein, His-tagged | E.coli | Rat | His | Met1-Cys293 |
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| PPP1R3A-7022M | Recombinant Mouse PPP1R3A Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| PPP1R3A-7022M-B | Recombinant Mouse PPP1R3A Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
PPP1R3A involved in several pathways and played different roles in them. We selected most pathways PPP1R3A participated on our site, such as Insulin signaling pathway,Insulin resistance, which may be useful for your reference. Also, other proteins which involved in the same pathway with PPP1R3A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Insulin signaling pathway | SHC3,SLC2A4,SREBF1,PPP1R3D,MKNK2B,INS1,ELK1,CALM,TRIP10,CALM4 |
| Insulin resistance | PPP1R3CA,SLC27A5,PTEN,IKBKB,GSK3AA,PPARGC1A,G6PC2,MAPK9,CREB1A,PTPRFB |
Protein Function
PPP1R3A has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by PPP1R3A itself. We selected most functions PPP1R3A had, and list some proteins which have the same functions with PPP1R3A. You can find most of the proteins on our site.
| Function | Related Protein |
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Interacting Protein
PPP1R3A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PPP1R3A here. Most of them are supplied by our site. Hope this information will be useful for your research of PPP1R3A.
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References
- Guo, WZ; Liu, HC; et al. Regulation of lovastatin on a key inflammation-related microRNA in myocardial cells. CHINESE MEDICAL JOURNAL 127:2977-2981(2014).
- Kamolrat, T; Gray, SR; et al. Fish oil positively regulates anabolic signalling alongside an increase in whole-body gluconeogenesis in ageing skeletal muscle. EUROPEAN JOURNAL OF NUTRITION 52:647-657(2013).
