PPM1K
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Official Full Name
protein phosphatase, Mg2+/Mn2+ dependent, 1K -
Overview
Protein phosphatase 1K, mitochondrial is an enzyme that in humans is encoded by the PPM1K gene. -
Synonyms
PPM1K;protein phosphatase, Mg2+/Mn2+ dependent, 1K;protein phosphatase 1K (PP2C domain containing);protein phosphatase 1K, mitochondrial;DKFZp761G058;hPTMP;PP2C type mitochondrial phosphoprotein phosphatase;PP2Ckappa;PP2Cm;protein phosphatase 2C kappa;PP2C domain containing protein phosphatase 1K;PP2C kappa;PP2C like mitochondrial protein;Protein phosphatase 2C isoform kappa;PTMP;PP2C-kappa;PP2C-like protein;PP2C-like mitochondrial protein;PP2C type mitochondrial phosphatase;PP2C domain-containing protein phosphatase 1K;PP2C-type mitochondrial phosphoprotein phosphatase;UG0882E07
Recombinant Proteins
- Human
- Zebrafish
- Rhesus macaque
- Mouse
- HEK293
- Mammalian Cell
- Human Cell
- HEK293T
- His
- Non
- Flag
- Myc&DDK
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| PPM1K-174H | Recombinant Human PPM1K, His-tagged | HEK293 | Human | His | 30-372 a.a. |
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| PPM1K-2103Z | Recombinant Zebrafish PPM1K | Mammalian Cell | Zebrafish | His |
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| PPM1K-3555R | Recombinant Rhesus monkey PPM1K Protein, His-tagged | Mammalian Cell | Rhesus macaque | His |
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| PPM1K-2957HCL | Recombinant Human PPM1K 293 Cell Lysate | HEK293 | Human | Non |
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| PPM1K-176H | Recombinant Human PPM1K Protein, DYKDDDDK-tagged | Human Cell | Human | Flag |
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| PPM1K-3245H | Recombinant Human PPM1K Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| PPM1K-3373R | Recombinant Rhesus Macaque PPM1K Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| PPM1K-3373R-B | Recombinant Rhesus Macaque PPM1K Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| Ppm1k-5051M | Recombinant Mouse Ppm1k Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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Involved Pathway
PPM1K involved in several pathways and played different roles in them. We selected most pathways PPM1K participated on our site, such as Branched-chain amino acid catabolism,Metabolism,Metabolism of amino acids and derivatives, which may be useful for your reference. Also, other proteins which involved in the same pathway with PPM1K were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Branched-chain amino acid catabolism | IVD,DBT,HIBADHA,HIBADH,ALDH9A1A.2,DLD,BCKDK |
| Metabolism of amino acids and derivatives | DAO,CKBA,AHCY,AZIN1B,NQO1,LSM1,DAO1,OAZ1,SLC6A12,CKMT1B |
| Metabolism | GPAT2,PAOX,MED19,GLTPA,Gpc2,ELOVL1A,PNP5B,SCO1,PPP1R2,GPHN |
Protein Function
PPM1K has several biochemical functions, for example, metal ion binding,protein binding,protein serine/threonine phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PPM1K itself. We selected most functions PPM1K had, and list some proteins which have the same functions with PPM1K. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| metal ion binding | ARMC1,ACAN,PLEKHF1,NDUFV1,RPP21,ITGB1BP3,GLRX3,CSH1,FIBCD1,ZNRF3 |
| protein serine/threonine phosphatase activity | CDC14B,PPP2R1A,ILKAP,PPP4C,MTMR4,PPP1CC,LCK,DUSP23A,PPA2,CDC14C |
| protein binding | NSMCE1,LASP1,TNKS2,TXNRD3,BET1,VCP,PTPMT1,AP3M1,MUL1,MEGF6 |
Interacting Protein
PPM1K has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PPM1K here. Most of them are supplied by our site. Hope this information will be useful for your research of PPM1K.
BIRC2;MYB
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References
- Lynch, CJ; Adams, SH; et al. Branched-chain amino acids in metabolic signalling and insulin resistance. NATURE REVIEWS ENDOCRINOLOGY 10:723-736(2014).
- Chan, WL; Yuo, CY; et al. Transcribed pseudogene psi PPM1K generates endogenous siRNA to suppress oncogenic cell growth in hepatocellular carcinoma. NUCLEIC ACIDS RESEARCH 41:3734-3747(2013).
