Pot1a
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Official Full Name
protection of telomeres 1A
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| POT1A-13133M | Recombinant Mouse POT1A Protein | Mammalian Cell | Mouse | His |
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| Pot1a-174M | Recombinant Mouse Pot1a Protein, MYC/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| POT1A-6948M | Recombinant Mouse POT1A Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| POT1A-6948M-B | Recombinant Mouse POT1A Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
Pot1a involved in several pathways and played different roles in them. We selected most pathways Pot1a participated on our site, such as Cell Cycle,Cellular Senescence,Cellular responses to stress, which may be useful for your reference. Also, other proteins which involved in the same pathway with Pot1a were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Chromosome Maintenance | NPM1,CENPH,CENPW,MLF1IP,CENPN,CENPQ,CENPA,MIS18A,DNA2,SMARCA5 |
| Cell cycle | MCM10,KNTC1,RBBP7,NPM1,MIS18A,SKP1,CDC25A,PKMYT1,CENPI,BORA |
| Cellular Senescence | MINK1,TERF2IP,RNF2,H1F0,SUZ12A,HMGA1B,CDKN2D,MAPKAPK2B,HIST1H1A,CEBPB |
| Meiotic synapsis | TERF1,STAG2,POT1,SYCE1,TEX12,SYNE2,SYNE1,FKBP6,TERF2,ACD |
| DNA Damage/Telomere Stress Induced Senescence | RAD50,HMGA1B,HMGA1,TINF2,HIST1H1A,TERF1,HIST1H1E,ASF1A,TERF2IP,HIST1H1D |
| Cellular responses to stress | MAPKAPK2B,CDK6,HIST2H3C,CBX8B,SCMH1,DYNLL2A,CEBPB,AMBRA1,PHC1,MAP1LC3C |
| Packaging Of Telomere Ends | POT1,TINF2,TERF2,TERF1,ACD |
| Mus musculus biological processes | SYNE2,SYCE2,MED11,SYCP1,KLF5,SUN2 |
Protein Function
Pot1a has several biochemical functions, for example, DEAD/H-box RNA helicase binding,DNA binding,G-rich strand telomeric DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Pot1a itself. We selected most functions Pot1a had, and list some proteins which have the same functions with Pot1a. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| G-rich strand telomeric DNA binding | CTC1,CDAN1,POT1 |
| telomerase inhibitor activity | PINX1,MCRS1,POT1 |
| single-stranded telomeric DNA binding | HNRNPA2B1,OBFC1,POT1 |
| telomeric DNA binding | PIF1,XRCC5,SMG6,NCL,TERT,TP53BP1,TINF2,TERF1,CDAN1,TERFA |
| protein binding | FES,COBL,PDE9A,POU4F1,KLB,HNRNPH3,BCL2L15,FBXO2,PPP6R2,UBE2D3 |
| DNA binding | ZNF577,EOMES,LIN54,APEX1,PRRX1B,GM14479,GABPA,MYCA,HMGB1B,HER1 |
| DEAD/H-box RNA helicase binding | POT1,ETV3,AKAP8L |
Interacting Protein
Pot1a has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Pot1a here. Most of them are supplied by our site. Hope this information will be useful for your research of Pot1a.
Tpp1;telomeric_dna_human_c-strand;Acd;Terf1
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