POP4
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Official Full Name
processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae) -
Overview
This gene encodes one of the protein subunits of the small nucleolar ribonucleoprotein complexes: the endoribonuclease for mitochondrial RNA processing complex and the ribonuclease P complex. The encoded protein is localized to the nucleus and associates directly with the RNA component of these complexes. This protein is involved in processing of precursor RNAs. Alternative splicing results in multiple transcript variants. -
Synonyms
POP4;RPP29;ribonuclease P protein subunit p29;hPOP4;EC 3.1.26.5;processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae)
Recombinant Proteins
- Human
- Mouse
- Zebrafish
- Chicken
- Rat
- E.coli
- Mammalian Cells
- HEK293
- His
- Non
- His&SUMO
- His&Fc&Avi
Involved Pathway
POP4 involved in several pathways and played different roles in them. We selected most pathways POP4 participated on our site, such as Gene Expression,RNA transport,Ribosome biogenesis in eukaryotes, which may be useful for your reference. Also, other proteins which involved in the same pathway with POP4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Ribosome biogenesis in eukaryotes | GNL3,MPHOSPH10,NAT10,RPP25L,UTP18,IMP3,XRN2,POP1,SBDS,NOP58 |
| tRNA processing | TRMT61A,TRMT5,PUS7,TSEN54,TYW1,TRMT44,WDR4,TRMT6,ZBTB8OS,TRMT11 |
| RNA transport | PABPC1B,EIF4A3,MAGOH2,KPNB1,EIF4G1A,SUMO1,RPP40,RPP30,GEMIN2,PABPC1 |
| tRNA processing in the nucleus | POP1,ELAC2,RPP40,TSEN15,POP7,TSEN54,XPOT,TSEN34,RPP14,C14orf166 |
| Gene Expression | ZNF192,ZNF468,TSEN2,YBX1,TNPO1,RARGA,VDRB,ZNF688,ZNF649,ZNF70 |
Protein Function
POP4 has several biochemical functions, for example, RNA binding,protein binding,contributes_to ribonuclease MRP activity. Some of the functions are cooperated with other proteins, some of the functions could acted by POP4 itself. We selected most functions POP4 had, and list some proteins which have the same functions with POP4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| RNA binding | PCBP2,ADARB1A,LSM5,AKAP1,HENMT1,KHDRBS3,IFIT3,SYNJ2,RPL27A,KHDC1C |
| ribonuclease P activity | RPP14,POP5,RPP38,RPP30,POP1,RPP40,POP7,RPP25 |
| protein binding | PABPC1,SNRPA1,PTPRR,GLDN,MPHOSPH6,ALG2,UHRF1,RBP7,MYH9,CLEC1B |
Interacting Protein
POP4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with POP4 here. Most of them are supplied by our site. Hope this information will be useful for your research of POP4.
RPP14;RPP38;POP5;POP1;RPP25;fabF;ssrna_ug;PRPF4;MYC;S100A4;RPL10;Ppp2ca
Resources
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References
- Porter, KA; Duffy, EB; et al. The CLRX.1/NOD24 (NLRP2P) pseudogene codes a functional negative regulator of NF-kappa B, pyrin-only protein 4. GENES AND IMMUNITY 15:392-403(2014).
- Chigeza, G; Mashingaidze, K; et al. Advanced cycle pedigree breeding in sunflower. I: Genetic variability and testcross hybrid performance for seed yield and other agronomic traits. EUPHYTICA 190:425-438(2013).
