POLR2H

  • Official Full Name

    polymerase (RNA) II (DNA directed) polypeptide H

  • Overview

    This gene encodes one of the essential subunits of RNA polymerase II that is shared by the other two eukaryotic DNA-directed RNA polymerases, I and III.

  • Synonyms

    POLR2H;polymerase (RNA) II (DNA directed) polypeptide H;DNA-directed RNA polymerases I, II, and III subunit RPABC3;RPB8;and III 17.1 kDa polypeptide;and III subunit ABC3;II;DNA-directed RNA polymerase II subunit H;DNA-directed RNA polymerases I;hRPB8;RNA polymerases I;RPAB3_HUMAN;RPB17;RPB8 homolog;OTTHUMP00000210505;OTTHUMP00000210507;OTTHUMP00000210508;OTTHUMP00000210509;OTTHUMP00000210511;OTTHUMP00000210512;RNA polymerases I, II,;RPABC3;hsRPB8

Recombinant Proteins

  • Mouse
  • Zebrafish
  • Chicken
  • Human
  • Cynomolgus
  • Mammalian Cells
  • E.coli
  • HEK293
  • His
  • GST
  • Non
  • DDK
  • Myc
  • Avi
  • Fc

    Involved Pathway

    POLR2H involved in several pathways and played different roles in them. We selected most pathways POLR2H participated on our site, such as Purine metabolism,Pyrimidine metabolism,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with POLR2H were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Metabolic pathways HSD3B1,PPOX,UMPS,UGT1A6B,CHIA,AMY1A,DPM3,ATP6V1D,CERS2,POLR2B
    Epstein-Barr virus infection EIF2AK3,ENTPD3,MAP2K6,CD58,TRAF6,PSMC2,TRAF1,NCOR2,POLR2D,POLR2G
    Pyrimidine metabolism POLD4,ENTPD1,DPYS,UCK2B,DHODH,NT5C1B-RDH14,DTYMK,CANT1B,CAD,POLE2
    RNA polymerase POLR3GLB,POLR3E,POLR2F,POLR2L,POLR2A,POLR2GL,POLR2K,POLR2G,POLR2I,ZNRD1
    Huntingtons disease POLR2F,ATP5H,COX6A2,Casp3,SDHB,CREB3L1,NRF1,COX7B,POLR2L,SLC25A4
    Purine metabolism NT5C2B,PDE9A,PDE8A,PKMA,POLA1,APRT,POLA2,RRM2B,POLE2,POLE3
    Cytosolic DNA-sensing pathway CCL4L1,Ifna11,POLR3G,IKBKE,RIPK1L,CASPA,ADAR,LOC100033925,IRF7,POLR3H

    Protein Function

    POLR2H has several biochemical functions, for example, DNA binding,contributes_to RNA polymerase I activity,contributes_to RNA polymerase II activity. Some of the functions are cooperated with other proteins, some of the functions could acted by POLR2H itself. We selected most functions POLR2H had, and list some proteins which have the same functions with POLR2H. You can find most of the proteins on our site.

    Function Related Protein
    contributes_to RNA polymerase II activity POLR2J2,POLR2A,POLR2J,POLR2B,POLR2F,POLR2K,POLR2E,POLR2L,POLR2J3,POLR2EB
    DNA binding ZNF643,ZNF18,RX2,PIAS1,POLE3,OTX1A,GZF1,CDK9,OASL,ZNF597
    contributes_to RNA polymerase III activity POLR1D,POLR2E,POLR3F,CRCP,POLR2EB,POLR3GLB,POLR3G,POLR2L,POLR3K,POLR3E
    contributes_to RNA polymerase I activity POLR2E,POLR1E,POLR2EB,POLR2L,POLR2K,POLR1D,POLR1A,ZNRD1,POLR1C,TWISTNB

    Interacting Protein

    POLR2H has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with POLR2H here. Most of them are supplied by our site. Hope this information will be useful for your research of POLR2H.

    MED19;MED26;EIF1B;NME2;CD40;IKBKE;NFKBIB;TRAF6;ubiG;ssdna_dtdg

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