POLR1E
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Official Full Name
polymerase (RNA) I polypeptide E, 53kDa -
Overview
DNA-directed RNA polymerase I subunit RPA49 is an enzyme that in humans is encoded by the POLR1E gene. -
Synonyms
POLR1E;polymerase (RNA) I polypeptide E, 53kDa;polymerase (RNA) I associated factor 1 , PRAF1;DNA-directed RNA polymerase I subunit RPA49;FLJ13390;FLJ13970;PAF53;RNA polymerase I associated factor 53;A49;DNA directed RNA polymerase I subunit RPA49;DNA-directed RNA polymerase I subunit E;FLJ 13390;POLR 1 E;Polymerase (RNA) I associated factor 1;Polymerase (RNA) I polypeptide E;PRAF1;RNA polymerase I associated factor 1;RNA polymerase I polypeptide E;RNA polymerase I subunit A49;RP11405L18.3;RNA polymerase I-associated factor 1;RNA polymerase I-associated factor 53;RP11-405L18.3
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| POLR1E-1840H | Recombinant Human POLR1E, GST-tagged | E.coli | Human | GST | C-term-317aa | |
| POLR1E-2864Z | Recombinant Zebrafish POLR1E | Mammalian Cells | Zebrafish | His |
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| POLR1E-3038HCL | Recombinant Human POLR1E 293 Cell Lysate | HEK293 | Human | Non |
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| Polr1e-4995M | Recombinant Mouse Polr1e Protein, Myc/DDK-tagged | HEK293 | Mouse | DDK&Myc |
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Involved Pathway
POLR1E involved in several pathways and played different roles in them. We selected most pathways POLR1E participated on our site, such as Purine metabolism,Pyrimidine metabolism,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with POLR1E were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Pyrimidine metabolism | NME3,CDA,NME1-NME2,CMPK2,CANT1A,TRR1,POLE3,POLR2E,NT5C,PNP |
| Metabolic pathways | BCAT2,B3GNT6,FBP1,ALG5,MCEE,ADH1,MVD,ATP5G3A,FUT7,CBR2 |
| RNA polymerase | POLR2J2,POLR2J3,POLR2E,POLR2GL,POLR2G,POLR2B,POLR2L,POLR3E,POLR3B,POLR2D |
| Purine metabolism | NT5C2A,ADCY1A,NUDT16,ADCY1B,Adcy4,PRPS1L1,POLR1C,POLD1,PNP5B,NME5 |
Protein Function
POLR1E has several biochemical functions, for example, DNA binding,contributes_to RNA polymerase I activity,RNA polymerase I transcription factor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by POLR1E itself. We selected most functions POLR1E had, and list some proteins which have the same functions with POLR1E. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| DNA binding | ZNF668,ZNF597,DLX2B,HIST1H2AC,ZNF823,ZNF625,POLR2J2,SCXB,ARX,ZFPM1 |
| RNA polymerase I transcription factor binding | CAV1 |
| contributes_to RNA polymerase I activity | POLR2E,POLR1C,POLR2L,POLR1A,POLR2H,TWISTNB,ZNRD1,POLR2K,POLR1D,POLR2F |
Interacting Protein
POLR1E has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with POLR1E here. Most of them are supplied by our site. Hope this information will be useful for your research of POLR1E.
q65zq1_human;IGF2BP3;POLR1C;EIF3H;POLR2E;DDX6;HNRNPA3;NFKBIB;CDC37;HDX;RB1CC1;RADIL;HNRNPAB;HNRNPUL1;TAF1D;q9h6s8_human;RNMTL1;QPCTL;SUN2
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