POFUT1
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Official Full Name
protein O-fucosyltransferase 1 -
Overview
This gene encodes a member of the glycosyltransferase O-Fuc family. This enzyme adds O-fucose through an O-glycosidic linkage to conserved serine or threonine residues in the epidermal growth factor-like repeats of a number of cell surface and secreted proteins. O-fucose glycans are involved in ligand-induced receptor signaling. Alternative splicing of this gene results in two transcript variants encoding different isoforms. -
Synonyms
POFUT1;protein O-fucosyltransferase 1;GDP-fucose protein O-fucosyltransferase 1;FUT12;KIAA0180;O Fuc T;O FUT;FUT 12;GDP fucose protein O fucosyltransferase 1;GDP fucose protein O fucosyltransferase1;O FucT 1;O FucT;O FucT1;O-FucT-1;OFuc T;OFucT;OFucT1;OFUT 1;OFUT;OFUT1;OFUT1_HUMAN;Peptide O fucosyltransferase 1;Peptide O fucosyltransferase1;Peptide-O-fucosyltransferase 1;Pofut 1;Protein O fucosyltransferase 1;Protein O fucosyltransferase1;o-fucosyltransferase protein;O-FUT;O-Fuc-T
Recombinant Proteins
- Zebrafish
- Rat
- Chicken
- Human
- Mouse
- Mammalian Cell
- E.coli
- HEK293
- HEK293T
- His
- Non
- His&Fc&Avi
- Myc&DDK
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| POFUT1-11738Z | Recombinant Zebrafish POFUT1 | Mammalian Cell | Zebrafish | His |
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| POFUT1-4558R | Recombinant Rat POFUT1 Protein | Mammalian Cell | Rat | His |
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| POFUT1-5997C | Recombinant Chicken POFUT1 | Mammalian Cell | Chicken | His |
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| POFUT1-7213H | Recombinant Human POFUT1, His-tagged | E.coli | Human | His | 27-388aa |
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| POFUT1-3057HCL | Recombinant Human POFUT1 293 Cell Lysate | HEK293 | Human | Non |
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| POFUT1-206H | Recombinant Human POFUT1 Protein, His-tagged | E.coli | Human | His | His238~Phe388 |
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| Pofut1-207M | Recombinant Mouse Pofut1 Protein, His-tagged | E.coli | Mouse | His | His243~Phe393 |
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| POFUT1-4218R | Recombinant Rat POFUT1 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| POFUT1-4218R-B | Recombinant Rat POFUT1 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| POFUT1-5152H | Recombinant Human POFUT1 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| Pofut1-986M | Recombinant Mouse Pofut1 Protein, MYC/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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Involved Pathway
POFUT1 involved in several pathways and played different roles in them. We selected most pathways POFUT1 participated on our site, such as Other types of O-glycan biosynthesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with POFUT1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Other types of O-glycan biosynthesis | ST3GAL3,FUT4,CHST10,POMT2,B3GALTLA,ST3GAL3B,FUT9,C3orf64,B3GAT2,GLT25D2 |
Protein Function
POFUT1 has several biochemical functions, for example, fucosyltransferase activity,peptide-O-fucosyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by POFUT1 itself. We selected most functions POFUT1 had, and list some proteins which have the same functions with POFUT1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| peptide-O-fucosyltransferase activity | POFUT2 |
| fucosyltransferase activity | UGGT1,GALNT18A,FUT1,FUT6,FUT9D,B3GNT8,GLT8D1,GTDC2,B3GNTL1,FUT9 |
Interacting Protein
POFUT1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with POFUT1 here. Most of them are supplied by our site. Hope this information will be useful for your research of POFUT1.
AKT2;H2AFX
POFUT1 Related Signal Pathway
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