PLEK
-
Official Full Name
pleckstrin -
Overview
Pleckstrin is a protein found in platelets. The name derives from platelet and leukocyte C kinase substrate and the KSTR string of amino acids. -
Synonyms
PLEK;pleckstrin;P47;platelet 47 kDa protein;FLJ27168
Recombinant Proteins
- Human
- Zebrafish
- Rat
- Chicken
- Mouse
- E.coli
- Mammalian Cells
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- His
- Non
- His&Fc&Avi
- Myc&DDK
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| PLEK-1773H | Recombinant Human PLEK, His-tagged | E.coli | Human | His | 1-350aa | |
| PLEK-11094Z | Recombinant Zebrafish PLEK | Mammalian Cells | Zebrafish | His |
|
|
| PLEK-28515TH | Recombinant Human PLEK | Wheat Germ | Human | Non | 110 amino acids |
|
| PLEK-30882TH | Recombinant Human PLEK | Wheat Germ | Human | Non | 350 amino acids |
|
| PLEK-4512R | Recombinant Rat PLEK Protein | Mammalian Cells | Rat | His |
|
|
| PLEK-497H | Recombinant Human PLEK, His tagged | E.coli | Human | His | 1-350 a.a. |
|
| PLEK-6426C | Recombinant Chicken PLEK | Mammalian Cells | Chicken | His |
|
|
| PLEK-3119HCL | Recombinant Human PLEK 293 Cell Lysate | HEK293 | Human | Non |
|
|
| PLEK-373HF | Recombinant Full Length Human PLEK Protein | In Vitro Cell Free System | Human | Full L. 350 amino acids |
|
|
| PLEK-4172R | Recombinant Rat PLEK Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
|
|
| PLEK-4172R-B | Recombinant Rat PLEK Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
|
||
| Plek-4923M | Recombinant Mouse Plek Protein, Myc/DDK-tagged | HEK293 | Mouse | Myc&DDK |
|
Involved Pathway
PLEK involved in several pathways and played different roles in them. We selected most pathways PLEK participated on our site, such as Hemostasis,Platelet activation, signaling and aggregation,Platelet degranulation, which may be useful for your reference. Also, other proteins which involved in the same pathway with PLEK were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Platelet activation, signaling and aggregation | CALU,CD9B,TRPC6A,MMRN1,F13A1B,STXBP3A,PRKCHB,GNA13B,FCER1GL,SPARC |
| Platelet degranulation | WDR1,TFA,HRG,CD9B,SERPINF2B,BRPF3,GAS6,MMRN1,CALU,MMRN2A |
| Hemostasis | IRF2A,HBB-Y,DOCK6,ZFPM2A,ANXA2A,G6b,HRG,PIK3R6,HMG20B,MMRN1 |
| Response to elevated platelet cytosolic Ca2+ | CD9B,F13A1A.1,HRG,SPARC,IGF2B,MMRN2A,CD9A,SERPINF2B,MMRN1,BRPF3 |
Protein Function
PLEK has several biochemical functions, for example, phosphatidylinositol-3,4-bisphosphate binding,protein binding,protein homodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PLEK itself. We selected most functions PLEK had, and list some proteins which have the same functions with PLEK. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | ORAI2,EDA2R,NQO1,MAMSTR,SPERT,RASSF4,SPRY1,S1PR2,IL17RE,ASIC1 |
| protein kinase C binding | PARD6A,GLRX3,GNB2L1,TRPV4,SDPR,DACT2,UGT1A7,AVPR1A,DACT3,PDLIM5 |
| protein homodimerization activity | CRYBA2,CEBPE,GSTZ1,Anks6,GSTA4,ADH5,GNPTG,LRP6,RAB11FIP4A,HLCS |
| phosphatidylinositol-3,4-bisphosphate binding | ARAP3,MYO1G,PHLDA3,ZFYVE1,ADAP2,TTPA,PLEKHA1,ANXA8,DAPP1,RAG2 |
Interacting Protein
PLEK has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PLEK here. Most of them are supplied by our site. Hope this information will be useful for your research of PLEK.
INPP5A;SDPR;PF4;THBS1;ACTN1;MSN
Resources
Related Services
Related Products
References
- Honarpisheh, H; Glusac, EJ; et al. Cytokeratin 20 expression in basaloid follicular hamartoma and infundibulocystic basal cell carcinoma. JOURNAL OF CUTANEOUS PATHOLOGY 41:916-921(2014).
- Jeon, SY; Kim, DC; et al. Expression Patterns of Gli-1, Pleckstrin Homology-Like Domain, Family A, Member 1, Transforming Growth Factor- beta 1/beta 2, and p63 in Sebaceous and Follicular Tumors. ANNALS OF DERMATOLOGY 26:713-721(2014).
