PLA1A
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Official Full Name
phospholipase A1 member A -
Overview
The protein encoded by this gene is a phospholipase that hydrolyzes fatty acids at the sn-1 position of phosphatidylserine and 1-acyl-2-lysophosphatidylserine. This secreted protein hydrolyzes phosphatidylserine in liposomes. Three transcript variants encoding different isoforms have been found for this gene. -
Synonyms
PLA1A;phospholipase A1 member A;ps PLA1;OTTHUMP00000215249;OTTHUMP00000215250;AA986889;NMD;OTTHUMP00000215248;Phosphatidylserine specific phospholipase A1;Phosphatidylserine specific phospholipase A1alpha;PSPLA 1;PSPLA1;phosphatidylserine-specific phospholipase A1alpha;PS-PLA1
Recombinant Proteins
- Zebrafish
- Mouse
- Human
- Rat
- Mammalian Cell
- E.coli
- Mammalian cells
- HEK293
- HEK293T
- His
- Non
- Flag
- His&Fc&Avi
- Myc&DDK
Involved Pathway
PLA1A involved in several pathways and played different roles in them. We selected most pathways PLA1A participated on our site, such as Ras signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PLA1A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Ras signaling pathway | IGF1,RASA3,CALM4,RAB5B,PLA2G4F,ABL2,FLT1,MAPK8,GRIN2A,INS1 |
Protein Function
PLA1A has several biochemical functions, for example, phosphatidylcholine 1-acylhydrolase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PLA1A itself. We selected most functions PLA1A had, and list some proteins which have the same functions with PLA1A. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| phosphatidylcholine 1-acylhydrolase activity | ABHD3,PLA2G16,LIPG |
Interacting Protein
PLA1A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PLA1A here. Most of them are supplied by our site. Hope this information will be useful for your research of PLA1A.
ARRB1
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References
- Guo, M; Pei, RJ; et al. Phosphatidylserine-Specific Phospholipase A1 Involved in Hepatitis C Virus Assembly through NS2 Complex Formation. JOURNAL OF VIROLOGY 89:2367-2377(2015).
- Kunduri, G; Yuan, C; et al. Phosphatidic acid phospholipase A1 mediates ER-Golgi transit of a family of G protein-coupled receptors. JOURNAL OF CELL BIOLOGY 206:79-95(2014).
