PKNOX2
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Official Full Name
PBX/knotted 1 homeobox 2 -
Overview
Homeodomain proteins are sequence-specific transcription factors that share a highly conserved DNA-binding domain and;play fundamental roles in cell proliferation, differentiation, and death. PKNOX2 belongs to the TALE (3-amino acid;loop extension) class of homeodomain proteins characterized by a 3-amino acid extension between alpha helices 1 and 2;within the homeodomain (Imoto et al., 2001 (PubMed 11549286)). -
Synonyms
PKNOX2;PBX/knotted 1 homeobox 2;homeobox protein PKNOX2;FLJ13074;Homeobox protein PREP 2;PBX/knotted homeobox 2;PREP2;OTTHUMP00000231418;OTTHUMP00000231419;OTTHUMP00000231420;homeobox protein PREP-2
Recombinant Proteins
- Human
- Mouse
- Chicken
- Zebrafish
- E.coli
- Mammalian Cells
- HEK293
- GST
- His
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| PKNOX2-1747H | Recombinant Human PKNOX2, GST-tagged | E.coli | Human | GST | C-122aa | |
| PKNOX2-12877M | Recombinant Mouse PKNOX2 Protein | Mammalian Cells | Mouse | His |
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| PKNOX2-5799C | Recombinant Chicken PKNOX2 | Mammalian Cells | Chicken | His |
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| PKNOX2-9461Z | Recombinant Zebrafish PKNOX2 | Mammalian Cells | Zebrafish | His |
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| PKNOX2-1364HCL | Recombinant Human PKNOX2 cell lysate | Human | Non |
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| PKNOX2-6790M | Recombinant Mouse PKNOX2 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| PKNOX2-6790M-B | Recombinant Mouse PKNOX2 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
PKNOX2 involved in several pathways and played different roles in them. We selected most pathways PKNOX2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PKNOX2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
PKNOX2 has several biochemical functions, for example, RNA polymerase II regulatory region sequence-specific DNA binding,actin filament binding,actin monomer binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PKNOX2 itself. We selected most functions PKNOX2 had, and list some proteins which have the same functions with PKNOX2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| RNA polymerase II regulatory region sequence-specific DNA binding | LEF1,GLIS1,ZNF691,CDX1A,NR1I3,RELB,FOXF1,H2AFY,PAX9,GATA5 |
| actin monomer binding | ABL2,MYL2,PFN4,NOS3,TMSB15B,TWF1,TMSB,COBLL1,MTSS1,PFN2 |
| actin filament binding | AJUBA,ADSSL1,DBNLB,FLNA,JUB,ACTN1,MYH10,MYH9A,WIPF3,MTSS1 |
Interacting Protein
PKNOX2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PKNOX2 here. Most of them are supplied by our site. Hope this information will be useful for your research of PKNOX2.
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