PKIA
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Official Full Name
protein kinase (cAMP-dependent, catalytic) inhibitor alpha -
Synonyms
PKIA;protein kinase (cAMP-dependent, catalytic) inhibitor alpha;9017;ENSG00000171033;PRKACN1;8q21.12;cAMP-dependent protein kinase inhibitor alpha;cAMP-dependent protein kinase inhibitor alpha;PKI-alpha;cAMP-dependent protein kinase inhibitor, muscle/brain isoform
Recombinant Proteins
- Human
- Mouse
- Rhesus macaque
- Rat
- Chicken
- E.coli
- Mammalian Cells
- HEK293
- GST
- His
- Non
- His&Fc&Avi
- Myc&DDK
Involved Pathway
PKIA involved in several pathways and played different roles in them. We selected most pathways PKIA participated on our site, such as Alcoholism, which may be useful for your reference. Also, other proteins which involved in the same pathway with PKIA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Alcoholism | HDAC10,HIST2H3A,HIST3H2A,HIST1H4G,H2AFZ,H2AFB3,HIST2H3C,HDAC8,HDAC7A,MAPK1 |
Protein Function
PKIA has several biochemical functions, for example, cAMP-dependent protein kinase inhibitor activity,protein binding,protein kinase A catalytic subunit binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PKIA itself. We selected most functions PKIA had, and list some proteins which have the same functions with PKIA. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein kinase A catalytic subunit binding | SOX9,PRKAR2B,GSK3A,KCNQ1,CSK,PRKAR1A,GSK3B,RYR2,PRKAR2A,PJA2 |
| protein binding | PECAM1,SLC26A3,MMP9,RABL2A,SIVA1,LGR5,FARS2,LCOR,Clec4n,ZFYVE27 |
| cAMP-dependent protein kinase inhibitor activity | PKIG,PRKAR1A,PRKAR2A,PRKAG2,PRKAR2B,PRKAR1B,PKIB |
Interacting Protein
PKIA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PKIA here. Most of them are supplied by our site. Hope this information will be useful for your research of PKIA.
CRM1;PASK;XPO1
Resources
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References
- Yun, JW; Kim, M; et al. Highly expressed protein kinase A inhibitor alpha and suppression of protein kinase A may potentiate acetaminophen-induced hepatotoxicity. TOXICOLOGY LETTERS 229:59-65(2014).
- Conway, AE; Scotland, PB; et al. A CALM-derived nuclear export signal is essential for CALM-AF10-mediated leukemogenesis. BLOOD 121:4758-4768(2013).
