PITX1
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Official Full Name
paired-like homeodomain 1 -
Overview
This gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. Members of this family are involved in organ development and left-right asymmetry. This protein acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin. [provided by RefSeq, Jul 2008] -
Synonyms
PITX1;paired-like homeodomain 1;BFT;CCF;POTX;PTX1;LBNBG;pituitary homeobox 1;pituitary homeo box 1;homeobox protein PITX1;pituitary otx-related factor;hindlimb expressed homeobox protein backfoot;hindlimb-expressed homeobox protein backfoot;paired-like homeodomain transcription factor 1
Recombinant Proteins
- Mouse
- Human
- Zebrafish
- Chicken
- Rat
- Mammalian Cells
- Wheat Germ
- E.coli
- In Vitro Cell Free System
- HEK293
- His
- Non
- SUMO
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| PITX1-12849M | Recombinant Mouse PITX1 Protein | Mammalian Cells | Mouse | His |
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| PITX1-28302TH | Recombinant Human PITX1 | Wheat Germ | Human | Non | 314 amino acids |
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| PITX1-29536TH | Recombinant Human PITX1 | Wheat Germ | Human | Non | 89 amino acids |
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| PITX1-3771Z | Recombinant Zebrafish PITX1 | Mammalian Cells | Zebrafish | His |
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| PITX1-4009C | Recombinant Chicken PITX1 | Mammalian Cells | Chicken | His |
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| PITX1-4476R | Recombinant Rat PITX1 Protein | Mammalian Cells | Rat | His |
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| PITX1-1358HCL | Recombinant Human PITX1 cell lysate | Human | Non |
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| PITX1-0261H | Recombinant Human PITX1 Protein (Arg90-Gln152), N-SUMO-tagged | E.coli | Human | SUMO | Arg90-Gln152 |
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| PITX1-372HF | Recombinant Full Length Human PITX1 Protein | In Vitro Cell Free System | Human | Full L. 314 amino acids |
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| PITX1-4136R | Recombinant Rat PITX1 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| PITX1-4136R-B | Recombinant Rat PITX1 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| PITX1-6769M | Recombinant Mouse PITX1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| PITX1-6769M-B | Recombinant Mouse PITX1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
PITX1 involved in several pathways and played different roles in them. We selected most pathways PITX1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PITX1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
PITX1 has several biochemical functions, for example, RNA polymerase II core promoter proximal region sequence-specific DNA binding,protein binding,transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PITX1 itself. We selected most functions PITX1 had, and list some proteins which have the same functions with PITX1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | SAMHD1,DCC,GAD2,SLC25A23,POLR1D,PCOLCE,FKBP2,SLN,HDC,POP7 |
| transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding | HIF1A,HMGA2,POU4F2,IRF1,POU2F2,GRHL1,DDIT3,CREB1,EGR1,ELK3 |
| transcriptional activator activity, RNA polymerase II transcription factor binding | CLOCK,SOX10,LMO2,GBX2,PPARA,WWP2,MED12,KLF4,NOTCH1,NR1H4 |
| RNA polymerase II core promoter proximal region sequence-specific DNA binding | TFAM,CDX4,SREBF2,FOXJ1,ZNF713,FOXJ2,PRDM1,RBPJB,CUX2,GATA4 |
Interacting Protein
PITX1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PITX1 here. Most of them are supplied by our site. Hope this information will be useful for your research of PITX1.
RBPMS;DVL3;RHOXF2
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