Picalm
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Official Full Name
phosphatidylinositol binding clathrin assembly protein
Recombinant Proteins
- Human
- Rhesus macaque
- Rat
- Mouse
- E.coli
- Mammalian Cell
- HEK293
- HEK293T
- Mammalian cells
- His
- Non
- His&Fc&Avi
- Myc&DDK
- Flag
Involved Pathway
Picalm involved in several pathways and played different roles in them. We selected most pathways Picalm participated on our site, such as Clathrin derived vesicle budding,Golgi Associated Vesicle Biogenesis,Membrane Trafficking, which may be useful for your reference. Also, other proteins which involved in the same pathway with Picalm were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Vesicle-mediated transport | ARCN1,SCFD1,MYO6B,BLOC1S3,CNO,PPP6R3,CD163,TRAPPC6BL,FTH1A,STXBP3 |
| trans-Golgi Network Vesicle Budding | BLOC1S4,HIP1R,DTNBP1,GAK,SNX9B,PUM1,TCEAL4,TFR1B,DTNBP1B,AP4B1 |
| Membrane Trafficking | YIPF6,SCFD1,GJA5,MYO6A,YKT6,TPD52,DTNBP1,TPD52L1,LMAN2,TRAPPC3 |
| Golgi Associated Vesicle Biogenesis | AP1S3A,CLINT1,SNX9A,PLDN,SNX9B,HIP1RB,BLOC1S1,NAPAA,PPIAL4A,BLOC1S3 |
| Clathrin derived vesicle budding | APPA,CTSZ,AP3S1,NECAP1,PPIAL4A,AP1S1,TFR1B,AP1S3A,SNX9A,CLINT1 |
Protein Function
Picalm has several biochemical functions, for example, 1-phosphatidylinositol binding,clathrin adaptor activity,clathrin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Picalm itself. We selected most functions Picalm had, and list some proteins which have the same functions with Picalm. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| clathrin adaptor activity | DAB2,LDLRAP1,ARRB1 |
| clathrin heavy chain binding | KIAA1199,CLTA,LDLR,GPR107,CLTB |
| 1-phosphatidylinositol binding | PLEKHA4,PLEKHA2,WDFY3,MCF2L,PICALMA,SYT1,ZFYVE9,ZFYVE1,FRMPD2,PLEKHA3 |
| clathrin binding | SYT6,SYT5B,SYT5,TOM1,SYT11B,HIP1,SYT1B,SYT17,SYT9B,DNER |
| protein binding | HIST1H1E,SIRT6,ADCY6,PIBF1,CCDC6,TRMT2B,C16orf70,TGFA,CDKAL1,MMACHC |
Interacting Protein
Picalm has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Picalm here. Most of them are supplied by our site. Hope this information will be useful for your research of Picalm.
Necap1;YBX1;ostA2;proC;q8cle5_yerpe;ppc;PELI2;WNK1;SEC16A;PIK3C2A;GAK;HIP1R;FN1;CLTA;CLTB;VCAM1;EPS15;CLTCL1
Picalm Related Signal Pathway
Resources
Related Services
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References
- Belcavello, L; Camporez, D; et al. Association of MTHFR and PICALM polymorphisms with Alzheimer's disease. MOLECULAR BIOLOGY REPORTS 42:611-616(2015).
- Li, HL; Yang, P; et al. Common variants at Bin1 are associated with sporadic Alzheimer's disease in the Han Chinese population. PSYCHIATRIC GENETICS 25:21-25(2015).
