PI4K2B
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Official Full Name
phosphatidylinositol 4-kinase type 2 beta -
Overview
Phosphatidylinositol 4-kinases (PI4Ks) phosphorylate phosphatidylinositol to generate phosphatidylinositol 4-phosphate;(PIP), an immediate precursor of several important signaling and scaffolding molecules. PIP itself may also have;direct functional and structural roles. PI4K2B is a primarily cytosolic PI4K that is recruited to membranes, where it;stimulates phosphatidylinositol 4,5-bisphosphate synthesis (Wei et al., 2002 (PubMed 12324459)). -
Synonyms
PI4K2B;phosphatidylinositol 4-kinase type 2 beta;phosphatidylinositol 4-kinase type 2-beta;FLJ11105;PI4KIIB;PIK42B;PI4KII-BETA;phosphatidylinositol 4-kinase type II-beta;phosphatidylinositol 4-kinase type-II beta
Recombinant Proteins
- Human
- Mouse
- Chicken
- Zebrafish
- Rat
- E.coli
- Sf9 Cells
- Insect Cells
- Mammalian Cells
- HEK293
- His
- GST
- Non
- DDK
- Myc
- Avi
- Fc
Involved Pathway
PI4K2B involved in several pathways and played different roles in them. We selected most pathways PI4K2B participated on our site, such as Inositol phosphate metabolism,Metabolic pathways,Phosphatidylinositol signaling system, which may be useful for your reference. Also, other proteins which involved in the same pathway with PI4K2B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Inositol phosphate metabolism | PLCB3,PIP4K2B,IP6K3,MTMR7,PLCG2,PTENB,PI4KB,MTMR1,NUDT10,INPP5K |
| Metabolic pathways | ALG14,MAN2A1,ADC,NDUFA2,GALCB,UGT1A4,POLR2J3,ALDH9A1,HSD3B2,GMPPAA |
| Phosphatidylinositol signaling system | PIK3C3,MTMR4,CALM2A,CALM2B,CDS2,PIK3R5,MTMR1A,MTM1,PRKCBA,SYNJ1 |
Protein Function
PI4K2B has several biochemical functions, for example, 1-phosphatidylinositol 4-kinase activity,ATP binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PI4K2B itself. We selected most functions PI4K2B had, and list some proteins which have the same functions with PI4K2B. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATP binding | VARS,MAPKAPK2B,CAMK2D2,KTI12,WEE1,PCCB,PFKL,CAMK2D1,HIPK3,PHKG2 |
| 1-phosphatidylinositol 4-kinase activity | PI4KA,PI4KAB,PI4KB,PI4K2A,PI4KAA |
Interacting Protein
PI4K2B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PI4K2B here. Most of them are supplied by our site. Hope this information will be useful for your research of PI4K2B.
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