PGBD1
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Official Full Name
piggyBac transposable element derived 1 -
Overview
The piggyBac family of proteins, found in diverse animals, are transposases related to the transposase of the canonical piggyBac transposon from the moth, Trichoplusia ni. This family also includes genes in several genomes, including human, that appear to have been derived from the piggyBac transposons. This gene belongs to the subfamily of piggyBac transposable element derived (PGBD) genes. The PGBD proteins appear to be novel, with no obvious relationship to other transposases, or other known protein families. This gene product is specifically expressed in the brain, however, its exact function is not known. Alternative splicing results in multiple transcript variants encoding the same protein. -
Synonyms
PGBD1;piggyBac transposable element derived 1;piggyBac transposable element-derived protein 1;dJ874C20.4;HUCEP 4;SCAND4;Cerebral protein 4;hucep-4;PGBD1_HUMAN;cerebral protein-4
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| PGBD1-3260HCL | Recombinant Human PGBD1 293 Cell Lysate | HEK293 | Human | Non |
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| Pgbd1-4818M | Recombinant Mouse Pgbd1 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| PGBD1-6677H | Recombinant Human PGBD1 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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Involved Pathway
PGBD1 involved in several pathways and played different roles in them. We selected most pathways PGBD1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PGBD1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
PGBD1 has several biochemical functions, for example, protein binding,scavenger receptor activity,sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PGBD1 itself. We selected most functions PGBD1 had, and list some proteins which have the same functions with PGBD1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transcription factor activity, sequence-specific DNA binding | ZNF202,TFE3,ZNF615,ATF4B2,NR1I3,HOXB2A,ASCL2,DLX6,PRDM1A,HLF |
| sequence-specific DNA binding | POU2F2,SPIC,MAF,BCL11AA,ELF2B,NKX2-6,SIX1B,TEFA,CREBL2,DMRT3A |
| scavenger receptor activity | GM106,SUSD2,TMPRSS4,TMPRSS4B,ENPP2,PRG4A,TMPRSS15,TMPRSS13B,CD6,SCARA3 |
| protein binding | KIF9,ROCK1,CISH,CD6,TLR3,CEP350,AGBL4,CTBP1,INMT,OIP5 |
Interacting Protein
PGBD1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PGBD1 here. Most of them are supplied by our site. Hope this information will be useful for your research of PGBD1.
ZSCAN22;MEOX2;ZNF24;NR4A1;SCAND1;TRAF2;ZNF446
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References
- Mutalip, SSM; Yunos, NM; et al. Mechanisms of Action of 17 beta H-neriifolin on its Anticancer Effect in SKOV-3 Ovarian Cancer Cell Line. ANTICANCER RESEARCH 34:4141-4151(2014).
- Zhang, Y; Lu, TL; et al. Replication of Association between Schizophrenia and Chromosome 6p21-6p22.1 Polymorphisms in Chinese Han Population. PLOS ONE 8:-(2013).
