PFN1
-
Official Full Name
profilin 1 -
Synonyms
PFN1;profilin 1;profilin-1;profilin I
Recombinant Proteins
- Human
- Mouse
- Rat
- Cynomolgus
- E.coli
- Mammalian Cells
- HEK293
- Mouse
- GST
- His
- T7
- Non
- Avi
- Fc
- DDK
- Myc
- Flag
Involved Pathway
PFN1 involved in several pathways and played different roles in them. We selected most pathways PFN1 participated on our site, such as Rap signaling pathway,Regulation of actin cytoskeleton,Shigellosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with PFN1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Shigellosis | RHOG,NFKB1,IKBKB,MAPK9,WAS,MAPK11,MAPK1,CD44,DIAPH1,RELA |
| Regulation of Actin Cytoskeleton | MYL12.2,FGF12,ITGB4,F2,GSNB,INSRR,PAK6B,PIP5K1BB,PTK2,DIAPH1 |
| Salmonella infection | CDC42L2,CDC42,NLRC4,CCL4,KLC1A,ARPC4L,MAPK12,CCL4L1,CASP1,LBP |
| Rap signaling pathway | PRKCZ,PIK3CB,PIK3CD,IGF1R,APBB1IP,CALML3,FGFR2,FGFR4,PDGFRA,FGF10 |
Protein Function
PFN1 has several biochemical functions, for example, Rho GTPase binding,actin binding,actin monomer binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PFN1 itself. We selected most functions PFN1 had, and list some proteins which have the same functions with PFN1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| proline-rich region binding | FAM59A,BAIAP2L1,GHR,BAIAP2,ABL1,TCERG1,CYLD,ABI2,YAP1,APBB1 |
| actin monomer binding | MKL1B,MYL4,PRKCE,ABL1,TWF2,TMSB10,COBL,PKNOX2,LIMA1,COBLL1 |
| phosphatidylinositol-4,5-bisphosphate binding | STXBP6L,SCIN,FAM123A,VIL1,PHLDA3,KCNJ1,JPH2,SESTD1,SNX21,FAM123B |
| adenyl-nucleotide exchange factor activity | HSPBP1,GRPEL2,GRPEL1,SIL1,PFN2 |
| Rho GTPase binding | ARHGEF2,FLNA,INF2,AKAP13,ROCK2B,DOCK9,ANTXR2A,ROCK2A,DOCK10,DAPK3 |
| actin binding | SMYHC1,SPTAN1,SCINLB,ADD1,FSCN1A,PTK2,MTSS1L,DMTN,BAIAP2L1,CNN3 |
| protein binding | TAL1,IKZF3,ZNF167,PEX11A,TRPV5,STK38L,CARD10,FOXO3,HOOK1,AQP1 |
| poly(A) RNA binding | HNRPLL,RPSA,HSP90AB1,SNRPG,QK,D19BWG1357E,YWHAE,IFIT5,ALDH18A1,HIST1H4E |
Interacting Protein
PFN1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PFN1 here. Most of them are supplied by our site. Hope this information will be useful for your research of PFN1.
Wasl;WASF1;SRPK1;Diaph1;YWHAZ;Bles03;Csnk1e;Akap12;ZNF16;ACTB;TLE1;RAD51;UNC119;CRMP1;tdh;RIF1
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