PFKFB3

  • Official Full Name

    6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3

  • Overview

    6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 is an enzyme that in humans is encoded by the PFKFB1 gene.

  • Synonyms

    PFKFB3;6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3;6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3;iPFK-2;PFK/FBPase 3;6PF-2-K/Fru-2,6-P2ase 3;renal carcinoma antigen NY-REN-56;6PF-2-K/Fru-2,6-P2ase brain/placenta-type isozyme;6-p

Recombinant Proteins

  • Human
  • Zebrafish
  • Rat
  • E.coli
  • Mammalian Cells
  • Sf9 Cells
  • Insect Cells
  • Wheat Germ
  • HEK293
  • His
  • GST
  • His&GST
  • Non
  • His&Fc&Avi
Cat.# Product name Source (Host) Species Tag Protein Length Price
PFKFB3-3284H Recombinant Human PFKFB3 protein, His-tagged E.coli Human His 243-520 aa
PFKFB3-24H Active Recombinant Human PFKFB3 protein, His-tagged E.coli Human His 2-520 a.a.
PFKFB3-12572Z Recombinant Zebrafish PFKFB3 Mammalian Cells Zebrafish His
PFKFB3-215H Recombinant Human PFKFB3, GST-tagged Sf9 Cells Human GST
PFKFB3-4392R Recombinant Rat PFKFB3 Protein Mammalian Cells Rat His
PFKFB3-518H Active Recombinant Human PFKFB3 Protein, His & GST-tagged Insect Cells Human His&GST 1-520 a.a.
PFKFB3-82912TH Recombinant Human PFKFB3, GST-tagged Wheat Germ Human Non
PFKFB3-82913TH Recombinant Human PFKFB3, GST-tagged Insect Cells Human Non 1-520 a.a.
PFKFB3-471HCL Recombinant Human PFKFB3 cell lysate Insect Cells Human Non
PFKFB3-4052R Recombinant Rat PFKFB3 Protein, His (Fc)-Avi-tagged HEK293 Rat His&Fc&Avi
PFKFB3-4052R-B Recombinant Rat PFKFB3 Protein Pre-coupled Magnetic Beads HEK293 Rat

    Involved Pathway

    PFKFB3 involved in several pathways and played different roles in them. We selected most pathways PFKFB3 participated on our site, such as Fructose and mannose metabolism,HIF- signaling pathway,AMPK signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PFKFB3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Fructose and mannose metabolism HK1,ENOSF1,HKDC1,HK2,PMM1,PFKP,ALDOB,FBP1B,PFKFB4L,AKR1B1L
    HIF- signaling pathway ARNT,Il6ra,IL6R,HKDC1,CAMK2D,Trf,RBX1,MAPK1,MKNK1,NOX3
    AMPK signaling pathway AKT1S1,RAB10,CREB3L1,STK11,PIK3R2,CREB1,CRTC2,PDPK1,PRKAB1,HMGCR

    Protein Function

    PFKFB3 has several biochemical functions, for example, 6-phosphofructo-2-kinase activity,ATP binding,fructose-2,6-bisphosphate 2-phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PFKFB3 itself. We selected most functions PFKFB3 had, and list some proteins which have the same functions with PFKFB3. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding OPLAH,CAMK2B1,UBE2L3B,CAMK4,UBE1Y1,PLK2B,DNAJA4,PRKG1A,EGFRA,MAP4K1
    fructose-2,6-bisphosphate 2-phosphatase activity C12orf5,PFKFB1,PFKFB4,TIGARA,TIGARB,PFKFB2
    6-phosphofructo-2-kinase activity PFKFB2,PFKFB4L,PFKFB4,PFKFB1,PFKFB2A

    Interacting Protein

    PFKFB3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PFKFB3 here. Most of them are supplied by our site. Hope this information will be useful for your research of PFKFB3.

    CUL2;maP3;q81sn0_bacan;q81va8_bacan;ARRB2;ARRB1

    Resources

    Research Area

    Carbohydrate Kinases
    Other Autophagy-related Proteins

    References

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    Q&As

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