PEX26
-
Official Full Name
peroxisomal biogenesis factor 26 -
Overview
This gene belongs to the peroxin-26 gene family. It is probably required for protein import into peroxisomes. It anchors PEX1 and PEX6 to peroxisome membranes, possibly to form heteromeric AAA ATPase complexes required for the import of proteins into peroxisomes. Defects in this gene are the cause of peroxisome biogenesis disorder complementation group 8 (PBD-CG8). PBD refers to a group of peroxisomal disorders arising from a failure of protein import into the peroxisomal membrane or matrix. The PBD group is comprised of four disorders: Zellweger syndrome (ZWS), neonatal adrenoleukodystrophy (NALD), infantile Refsum disease (IRD), and classical rhizomelic chondrodysplasia punctata (RCDP). Alternatively spliced transcript variants have been identified for this gene. -
Synonyms
PEX26;peroxisomal biogenesis factor 26;peroxisome biogenesis factor 26;peroxisome assembly protein 26;FLJ20695;AI85321;4632428M11Rik;OTTMUSP00000033411;OTTMUSP00000033413;Peroxin 26;Peroxisome biogenesis disorder, complementation group 8;Peroxisome biogenesis disorder, complementation group A;PEX 26;Pex26pM1T;peroxin-26;PEX26M1T
Recombinant Proteins
- Zebrafish
- Mouse
- Human
- Rhesus macaque
- Cynomolgus
- Mammalian Cells
- E.coli
- HEK293
- His
- Non
- GST
- Avi
- Fc
Involved Pathway
PEX26 involved in several pathways and played different roles in them. We selected most pathways PEX26 participated on our site, such as Peroxisome, which may be useful for your reference. Also, other proteins which involved in the same pathway with PEX26 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Peroxisome | PEX3,AGPS,MVK,DECR2,CRATA,MPV17,AGXTB,CRAT,GSTK1,ANI_1_2390104 |
Protein Function
PEX26 has several biochemical functions, for example, ATPase binding,protein C-terminus binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PEX26 itself. We selected most functions PEX26 had, and list some proteins which have the same functions with PEX26. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ATPase binding | ATP6V0A4,SNX10,ATP6V0A2,ANK2,NOP58,EZR,DNAJC10,NKAIN1,ATP6V0A1A,GABARAPL2 |
| protein complex binding | PLK2,KRAS,TG,DRD1A,NDUFA4,YWHAB,PRKACA,ARRB2,LEPRE1,VAMP2 |
| protein binding | NEIL2,HTRA2,RBBP6,ZNF256,CDKN1A,FAM125B,MAP4K5,SRSF1,DCPS,CNOT8 |
| protein C-terminus binding | PEX12,ERCC2,VGLL2,CTGF,PFKM,PROP1,MED12,ATP1B1,MIF4GD,TFCP2 |
Interacting Protein
PEX26 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PEX26 here. Most of them are supplied by our site. Hope this information will be useful for your research of PEX26.
SUFU;PEX19;PEX3;q81n96_bacan;PEX1;PEX6
Resources
Related Services
Related Products
References
