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PDXP

  • Official Full Name

    pyridoxal (pyridoxine, vitamin B6) phosphatase

  • Overview

    Pyridoxal 5-prime-phosphate (PLP) is the active form of vitamin B6 that acts as a coenzyme in maintaining biochemical;homeostasis. The preferred degradation route from PLP to 4-pyridoxic acid involves the dephosphorylation of PLP by;PDXP (Jang et al., 2003 (PubMed 14522954)).

  • Synonyms

    PDXP;pyridoxal (pyridoxine, vitamin B6) phosphatase;pyridoxal phosphate phosphatase;dJ37E16.5;FLJ32703;chronophin;PLP phosphatase;CIN;PLP

Recombinant Proteins

  • Human
  • Mouse
  • E.coli
  • Insect Cell
  • Yeast
  • GST
  • His
  • His&SUMO
Cat.# Product name Source (Host) Species Tag Protein Length Price
PDXP-1884H Recombinant Human PDXP protein, GST-tagged E.coli Human GST 115-230 aa
PDXP-2856H Recombinant Human PDXP protein, His-tagged E.coli Human His 115 - 230 aa
PDXP-12604M Recombinant Mouse Pdxp protein, His/Sumo-tagged E.coli Mouse His&SUMO 1-292 aa
PDXP-1324H Recombinant Human PDXP Protein, His-tagged Insect Cell Human His 1-296 a.a.
PDXP-2762H Recombinant Human PDXP, His-tagged E.coli Human His
PDXP-30082TH Recombinant Human PDXP, His-tagged E.coli Human His 296 amino acids
PDXP-2078H Recombinant Human PDXP Protein (1-296 aa), His-tagged Yeast Human His 1-296 aa
PDXP-2491M Recombinant Mouse PDXP Protein (1-292 aa), His-tagged Yeast Mouse His 1-292 aa

    Involved Pathway

    PDXP involved in several pathways and played different roles in them. We selected most pathways PDXP participated on our site, such as Vitamin B metabolism,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with PDXP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Metabolic pathways GPI1,ACACA,CYP3A7-CYP3AP1,ATP5E,PKM2,AGPAT6,B4GALT3,HSD11B1,GLS2,HYKK
    Vitamin B metabolism PDXK,AOX4,AOX2P,PHOSPHO2,PSAT1,PDXKA,AOX1,AOX3L1,PNPO,AOX3

    Protein Function

    PDXP has several biochemical functions, for example, heat shock protein binding,magnesium ion binding,phosphoprotein phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PDXP itself. We selected most functions PDXP had, and list some proteins which have the same functions with PDXP. You can find most of the proteins on our site.

    Function Related Protein
    protein binding TREX1,CALCA,KIAA1279,ATF4,KIR2DL1,ALDH1A2,MICU1,CNTF,PRH1,UBE2F
    phosphoprotein phosphatase activity PPP3CB,SSH2,PTPN11B,PTEN,MTM1,TIMM50,PHLPP1,SSH1,PPP1CAB,PPM1BB
    phosphoserine phosphatase activity PSPH,DUSP26
    magnesium ion binding ADSS,LHPP,NIM1K,IDH2,PKMA,IMPA1,PKMB,HPRT1L,MAPK12,CERK
    heat shock protein binding HSPA8,DNAJA3A,DLST,CDC37L1,GRXCR2,DNAJA4,GM5506,DNAJB6,EEF1D,FKBP4
    pyridoxal phosphatase activity PHOSPHO2

    Interacting Protein

    PDXP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PDXP here. Most of them are supplied by our site. Hope this information will be useful for your research of PDXP.

    Arrb1;STK11

    Resources

    Research Area

    Multiple Sclerosis and Myelin Related Molecules
    Glial Lineage Markers

    References

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