PARP14
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Official Full Name
poly (ADP-ribose) polymerase family, member 14 -
Overview
Poly(ADP-ribosyl)ation is an immediate DNA damage-dependent posttranslational modification of histones and other;nuclear proteins that contributes to the survival of injured proliferating cells. PARP14 belongs to the superfamily of;enzymes that perform this modification (Ame et al., 2004 (PubMed 15273990)). -
Synonyms
PARP14;poly (ADP-ribose) polymerase family, member 14;poly [ADP-ribose] polymerase 14;KIAA1268;pART8;collaborator of STAT6;B-aggressive lymphoma 2;b aggressive lymphoma protein 2;BAL2;PARP-14
Recombinant Proteins
- Mouse
- Human
- Mammalian Cell
- Sf9 Insect Cell
- E.coli
- Yeast
- Insect Cell
- HEK293
- His
- His&GST
- Non
- His&Strep
- His&Myc
- Fc
- His&Fc&Avi
Involved Pathway
PARP14 involved in several pathways and played different roles in them. We selected most pathways PARP14 participated on our site, such as IL4-mediated signaling events, which may be useful for your reference. Also, other proteins which involved in the same pathway with PARP14 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
---|---|
IL4-mediated signaling events | EGR2,NIPAL1,TFF3,DOK2,IgG3,MYBL1,CCL26,IRF4,RETNLB,MYB |
Protein Function
PARP14 has several biochemical functions, for example, NAD+ ADP-ribosyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PARP14 itself. We selected most functions PARP14 had, and list some proteins which have the same functions with PARP14. You can find most of the proteins on our site.
Function | Related Protein |
---|---|
NAD+ ADP-ribosyltransferase activity | PARP16,PARP9,ART1,PARP15,GIG2H,PARP4,SIRT6,PARP1,GIG2L,GIG2Q |
Interacting Protein
PARP14 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PARP14 here. Most of them are supplied by our site. Hope this information will be useful for your research of PARP14.
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