PALLD
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Official Full Name
palladin, cytoskeletal associated protein -
Overview
This gene encodes a cytoskeletal protein that is required for organizing the actin cytoskeleton. The protein is a component of actin-containing microfilaments, and it is involved in the control of cell shape, adhesion, and contraction. Polymorphisms in this gene are associated with a susceptibility to pancreatic cancer type 1, and also with a risk for myocardial infarction. Alternative splicing results in multiple transcript variants. -
Synonyms
PALLD;palladin, cytoskeletal associated protein;palladin;CGI 151;KIAA0992;SIH002;myoneurin;sarcoma antigen NY-SAR-77;MYN;PNCA1;CGI151;CGI-151;FLJ22190;FLJ38193;FLJ39139;FLJ61376
Recombinant Proteins
- Human
- Mouse
- E.coli
- Mammalian Cells
- HEK293
- GST
- His
- His&T7
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| PALLD-1517H | Recombinant Human PALLD, GST-tagged | E.coli | Human | GST | C-term-385aa | |
| PALLD-12326M | Recombinant Mouse PALLD Protein | Mammalian Cells | Mouse | His |
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| PALLD-7150H | Recombinant Human PALLD protein, His & T7-tagged | E.coli | Human | His&T7 | Phe1137~Leu1383 |
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| PALLD-469HCL | Recombinant Human PALLD lysate | HEK293 | Human | Non |
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| PALLD-6479M | Recombinant Mouse PALLD Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| PALLD-6479M-B | Recombinant Mouse PALLD Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| PALLD-711H | Recombinant Human PALLD protein, His-tagged | E.coli | Human | His | Phe881-Tyr990 |
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Involved Pathway
PALLD involved in several pathways and played different roles in them. We selected most pathways PALLD participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PALLD were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
PALLD has several biochemical functions, for example, actin binding,muscle alpha-actinin binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PALLD itself. We selected most functions PALLD had, and list some proteins which have the same functions with PALLD. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| actin binding | SHROOM3,XIRP2,ACE,MYH6,FSCN2,WASLB,PPP1R9B,SPTB,MYLK,TBC1D21 |
| muscle alpha-actinin binding | LDB3,MYPN,NRAP,PKD2,PKD2L1,TTN,PDLIM2 |
| protein binding | SLAMF6,HNRNPR,ALOX5,CDK5R2,ZNF18,a,GNB1,COG4,NR1D1,KCNA2 |
Interacting Protein
PALLD has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PALLD here. Most of them are supplied by our site. Hope this information will be useful for your research of PALLD.
SORBS2;SRC;NCKIPSD;PDLIM3;katG;MYO1C;FLNA;Nedd1;LLGL2;Mib1;SKA3;MYO19
Resources
Research Area
Phospholipases, Small GTPases, and Other Molecules in the Akt PathwayFocal Adhesion Adaptor and Scaffold Proteins
Related Services
Related Products
References
- Nguyen, NUN; Liang, VR; et al. Actin-associated protein palladin is required for migration behavior and differentiation potential of C2C12 myoblast cells. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 452:728-733(2014).
- von Nandelstadh, P; Gucciardo, E; et al. Actin-associated protein palladin promotes tumor cell invasion by linking extracellular matrix degradation to cell cytoskeleton. MOLECULAR BIOLOGY OF THE CELL 25:2556-2570(2014).
