PABPC4
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Official Full Name
poly(A) binding protein, cytoplasmic 4 (inducible form) -
Overview
PolyA-binding protein (PABP) is a ubiquitous RNA binding protein that contains 4 RNA recognition motifs and a proline-rich C-terminal domain responsible for protein-protein interaction. It is an important regulator of mRNA stability and translation. PABPC -
Synonyms
PABPC4;poly(A) binding protein, cytoplasmic 4 (inducible form);polyadenylate-binding protein 4;APP 1;iPABP;PABP-4;poly(A)-binding protein 4;activated-platelet protein 1;inducible poly(A)-binding protein;APP1;APP-1;PABP4;FLJ43938
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| PABPC4-1504H | Recombinant Human PABPC4 protein, His-tagged | E.coli | Human | His | 285-631 aa | |
| PABPC4-11444Z | Recombinant Zebrafish PABPC4 | Mammalian Cell | Zebrafish | His |
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| PABPC4-1271HCL | Recombinant Human PABPC4 cell lysate | Human | Non |
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| PABPC4-4390H | Recombinant Human PABPC4 protein | E.coli | Human | Non | 1-644aa |
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Involved Pathway
PABPC4 involved in several pathways and played different roles in them. We selected most pathways PABPC4 participated on our site, such as RNA transport,mRNA surveillance pathway,RNA degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with PABPC4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| mRNA surveillance pathway | NXF2,PABPC1A,SSU72,PPP1CA,PPP2R2BB,PPP2R5B,GSPT1,PPP2R5D,CPSF1,PPP2R2A |
| RNA transport | TACC3,THOC2,RPP38,SIP1,GEMIN4,EIF4G1A,POP4,MAGOH,ALYREF,FXR1 |
| RNA degradation | TOB2,DHX36,LSM8,PFKMB,EDC3,LSM7,PABPC1A,MPHOSPH6,EXOSC3,DCP2 |
Protein Function
PABPC4 has several biochemical functions, for example, nucleotide binding,poly(A) RNA binding,poly(A) binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PABPC4 itself. We selected most functions PABPC4 had, and list some proteins which have the same functions with PABPC4. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | ICAM5,TTC12,TTC33,WTAP,TBC1D19,RTN3,MED28,HSPB2,ZNF843,SSX2 |
| poly(U) RNA binding | MSI2,HNRNPH1,KHDRBS1,PATL2,KHDRBS2,HNRNPC,RBM11,PATL1,PNPT1,DIS3L2 |
| poly(A) binding | PAIP2B,ZC3H14,DDX3X,KHDRBS2,RBPMS,HNRPDL,PABPC1,KHDRBS1,HNRNPDL,TIA1 |
| poly(A) RNA binding | MRPS21,DDX24,PPP1R10,YBX1,UTP15,PCSK9,TIAL1,HNRNPH1,RBM15B,CCAR1 |
| nucleotide binding | RTEL1,UBE1Y1,PRKG1A,CENPE,SMYHC1,NAIP6,TIA1,GNAO1A,GNA15.1,ATP2A1L |
Interacting Protein
PABPC4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PABPC4 here. Most of them are supplied by our site. Hope this information will be useful for your research of PABPC4.
YWHAZ;PHLDA1;SRPK2;PPM1B;HNF4A;ARF6;IKBKE;Klc1;PINX1;TNFRSF10D;PUF60;SMAD9;XRN1;15-deoxy-delta(12,14;midostaurin;NS1
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