otulin
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Official Full Name
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| OTULIN-2512H | Recombinant Human OTULIN protein, His-tagged | E.coli | Human | His | 139-352 aa | |
| OTULIN-157H |
Active Recombinant Human OTULIN, GST-tagged
|
E.coli | Human | GST | 1-352 a.a. |
|
| OTULIN-3666H | Recombinant Human OTULIN Protein, GST-tagged | Wheat Germ | Human | GST |
|
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| OTULIN-252HCL | Recombinant Human OTULIN lysate | HEK293 | Human | Non |
|
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| OTULIN-357H | Recombinant Human OTULIN Protein, His-tagged | E.coli | Human | His |
|
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| OTULIN-4460HF | Recombinant Full Length Human OTULIN Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 214 amino acids |
|
Involved Pathway
otulin involved in several pathways and played different roles in them. We selected most pathways otulin participated on our site, such as Death Receptor Signalling,Regulation of TNFR1 signaling,Signal Transduction, which may be useful for your reference. Also, other proteins which involved in the same pathway with otulin were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Signal Transduction | CDC73,STARD13,RDH14B,ADCYAP1B,PNOCB,ZFPM2B,RGS14,NEDD8,INSL3,CRABP1B |
| Regulation of TNFR1 signaling | USP4,USP2,FAM105B,TAX1BP1,TAX1BP1B,CLIP3,OTULINB,SHRPRBCK1R,RBCK1,SHARPIN |
| Death Receptor Signalling | FAM105B,USP4,RNF31,CYLD,SHRPRBCK1R,GNB2L1,USP2,RBCK1,SHARPIN,TAX1BP1 |
| TNF signaling | USP4,RBCK1,RNF31,OTUD7B,TAX1BP1,FAM105B,SHARPIN,OTULINB,SHRPRBCK1R,TAX1BP1B |
Protein Function
otulin has several biochemical functions, for example, cysteine-type peptidase activity,protein binding,ubiquitin-specific protease activity. Some of the functions are cooperated with other proteins, some of the functions could acted by otulin itself. We selected most functions otulin had, and list some proteins which have the same functions with otulin. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| cysteine-type peptidase activity | USP12A,SENP3A,USP43A,CAPN5A,CTSBA,USP27X,CTSSA,CAPN3B,CAPN1B,CTSJ |
| ubiquitin-specific protease activity | OTUD4,USP2A,USP22,MYSM1,CYLD,USP45,USP13,USP50,USP14,USP31 |
| protein binding | VIP,NMB,LIMA1,FSHB,TBCEL,ZNF317,ZSCAN1,CD163,CCDC43,CDKN2A |
Interacting Protein
otulin has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with otulin here. Most of them are supplied by our site. Hope this information will be useful for your research of otulin.
DAZAP2;FAM168A;DVL2;SNW1
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References
- Chen, YF; Wang, LF; et al. An ultrasensitive system for measuring the USPs and OTULIN activity using Nanoluc as a reporter. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 455:178-183(2014).
- Fiil, BK; Gyrd-Hansen, M; et al. Met1-linked ubiquitination in immune signalling. FEBS JOURNAL 281:4337-4350(2014).
