OTUB2
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Official Full Name
OTU domain, ubiquitin aldehyde binding 2 -
Overview
This gene encodes one of several deubiquitylating enzymes. Ubiquitin modification of proteins is needed for their stability and function; to reverse the process, deubiquityling enzymes remove ubiquitin. This protein contains an OTU domain and binds Ubal (ubiquitin aldehyde); an active cysteine protease site is present in the OTU domain. -
Synonyms
OTUB2;OTU domain, ubiquitin aldehyde binding 2;C14orf137, chromosome 14 open reading frame 137;ubiquitin thioesterase OTUB2;FLJ21916;MGC3102;C14orf137;Deubiquitinating enzyme OTUB2;OTB2;OTU domain containing ubiquitin aldehyde binding protein 2;OTU domain-containing ubiquitin aldehyde-binding protein 2;OTU2;OTUB2_HUMAN;Otubain 2;Otubain-2;Ubiquitin specific processing protease OTUB2;Ubiquitin specific protease otubain 2;Ubiquitin-specific-processing protease OTUB2;ubiquitin-specific protease otubain 2
Recombinant Proteins
- Human
- Mouse
- E.coli
- HEK293
- HEK293T
- His
- Non
- GST
- Myc&DDK
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| OTUB2-174H | Recombinant Human OTUB2, His-tagged | E.coli | Human | His |
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| OTUB2-2534H | Recombinant Human OTUB2 protein, His-tagged | E.coli | Human | His | 1-234 a.a. |
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| OTUB2-30525TH | Recombinant Human OTUB2, His-tagged | E.coli | Human | His | 234 amino acids |
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| OTUB2-64H | Recombinant Human OTUB2, His-tagged | E.coli | Human | His |
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| OTUB2-3515HCL | Recombinant Human OTUB2 293 Cell Lysate | HEK293 | Human | Non |
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| OTUB2-13HFL | Active Recombinant Full Length Human OTUB2 Protein, N-His tagged | E.coli | Human | His | Full L. Full Length |
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| OTUB2-353H | Recombinant Human OTUB2 Protein | E.coli | Human | Non |
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| OTUB2-354H | Recombinant Human OTUB2 Protein, GST-tagged | E.coli | Human | GST |
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| Otub2-4625M | Recombinant Mouse Otub2 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| OTUB2-4847H | Recombinant Human OTUB2 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| OTUB2-5173H | Recombinant Human OTUB2 Protein (Met1-His234), N-Gst tagged | E.coli | Human | GST | Met1-His234 |
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Involved Pathway
OTUB2 involved in several pathways and played different roles in them. We selected most pathways OTUB2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with OTUB2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
OTUB2 has several biochemical functions, for example, NEDD8-specific protease activity,protein binding,ubiquitin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by OTUB2 itself. We selected most functions OTUB2 had, and list some proteins which have the same functions with OTUB2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| NEDD8-specific protease activity | OTUB1B,OTUB1,OTUB1A |
| protein binding | ETNK1,SERTAD1,CCDC13,ZBED4,ZNF227,EMP1,UBE2E2,DNPEP,MARCH10,GAST |
| ubiquitin binding | CXCR4,NUP62,BCL10,OTUB1B,KIF18A,TOP2A,AUP1,SPRTN,OTUB1A,CRY1 |
| ubiquitin-specific protease activity | USP37,DUB1,USP12,BRCC3,USP9,OTUD7A,USP20,USP27X,UCHL3,USP34 |
Interacting Protein
OTUB2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with OTUB2 here. Most of them are supplied by our site. Hope this information will be useful for your research of OTUB2.
MID1;REL;TP53BP2;CPSF6;SIAH1;FAM168A;ARRDC3
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