OTOS
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Official Full Name
otospiralin -
Overview
Otospiralin is synthesized by nonsensory cells (fibrocytes) of the inner ear, and downregulation of otospiralin in;guinea pigs leads to deafness (Lavigne-Rebillard et al., 2003 (PubMed 12687421)). -
Synonyms
OTOS;otospiralin;OTOSP;OTOSP_HUMAN
Recombinant Proteins
- Rhesus macaque
- Rat
- Zebrafish
- Human
- Mouse
- Mammalian Cell
- HEK293
- HEK293T
- His
- His&Fc&Avi
- Myc&DDK
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| OTOS-3259R | Recombinant Rhesus monkey OTOS Protein, His-tagged | Mammalian Cell | Rhesus macaque | His |
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| OTOS-4217R | Recombinant Rat OTOS Protein | Mammalian Cell | Rat | His |
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| OTOS-8512Z | Recombinant Zebrafish OTOS | Mammalian Cell | Zebrafish | His |
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| OTOS-3077R | Recombinant Rhesus Macaque OTOS Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| OTOS-3077R-B | Recombinant Rhesus Macaque OTOS Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| OTOS-3879R | Recombinant Rat OTOS Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| OTOS-3879R-B | Recombinant Rat OTOS Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| OTOS-449H | Recombinant Human OTOS Protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
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| Otos-4624M | Recombinant Mouse Otos Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| OTOS-5418H | Recombinant Human OTOS Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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Involved Pathway
OTOS involved in several pathways and played different roles in them. We selected most pathways OTOS participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with OTOS were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
OTOS has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by OTOS itself. We selected most functions OTOS had, and list some proteins which have the same functions with OTOS. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
Interacting Protein
OTOS has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with OTOS here. Most of them are supplied by our site. Hope this information will be useful for your research of OTOS.
Resources
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References
- Spracklen, TF; Whitehorn, H; et al. Genetic variation in Otos is associated with cisplatin-induced ototoxicity. PHARMACOGENOMICS 15:1667-1676(2014).
- Decourt, B; Hillman, D; et al. Is otospiralin inner ear specific? Evidence for its expression in mouse brain. INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE 27:87-96(2009).
