NUDC
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Official Full Name
nuclear distribution gene C homolog (A. nidulans) -
Overview
This gene encodes a nuclear distribution protein that plays an essential role in mitosis and cytokinesis. The encoded;protein is involved in spindle formation during mitosis and in microtubule organization during cytokinesis.;Pseudogenes of this gene are found on chromosome 2. -
Synonyms
NUDC;nuclear distribution gene C homolog (A. nidulans);nuclear distribution gene C (A.nidulans) homolog;nuclear migration protein nudC;HNUDC;MNUDC;MNUDC protein;NPD011;Nuclear distribution gene C homolog;Nuclear distribution protein C homolog;NUDC_HUMAN;OTTHUMP00000004405;SIG 92;SIG92
Recombinant Proteins
- Zebrafish
- Chicken
- Rat
- Human
- E.coli
- Mouse
- Mammalian Cells
- HEK293
- E.coli
- His
- Non
- T7
- Avi
- Fc
- DDK
- Myc
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| NUDC-11160Z | Recombinant Zebrafish NUDC | Mammalian Cells | Zebrafish | His |
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| NUDC-1456C | Recombinant Chicken NUDC | Mammalian Cells | Chicken | His |
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| NUDC-4112R | Recombinant Rat NUDC Protein | Mammalian Cells | Rat | His |
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| NUDC-645H | Recombinant Human NUDC Protein, His-tagged | HEK293 | Human | His | 1-331 a.a. |
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| NUDC-3658HCL | Recombinant Human NUDC 293 Cell Lysate | HEK293 | Human | Non |
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| NUDC-1706H | Recombinant Human NUDC protein, His & T7-tagged | E.coli | Human | His&T7 | Ala167~Ser298 |
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| NUDC-3773R | Recombinant Rat NUDC Protein, His (Fc)-Avi-tagged | HEK293 | Rat | Avi&Fc&His |
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| NUDC-3773R-B | Recombinant Rat NUDC Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| NUDC-3982H | Recombinant Human NUDC Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293 | Human | DDK&Myc |
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| nudC-4443E | Recombinant Escherichia coli O157:H7 nudC protein, His-tagged | E.coli | E.coli | His | 1-257aa |
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| Nudc-4530M | Recombinant Mouse Nudc Protein, Myc/DDK-tagged | HEK293 | Mouse | DDK&Myc |
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Involved Pathway
NUDC involved in several pathways and played different roles in them. We selected most pathways NUDC participated on our site, such as Cell Cycle,Cell Cycle, Mitotic,Lissencephaly gene (LIS1) in neuronal migration and development, which may be useful for your reference. Also, other proteins which involved in the same pathway with NUDC were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Mitotic Prometaphase | CENPN,PDS5B,KNTC1,SKA2,NDEL1B,NDC80,CENPL,CENPP,CENPH,NCAPD2 |
| Cell cycle | NDEL1B,ITGB3BP,CSNK1D,TP53,NEK2,ATM,SPC24,CDKN1B,AURKB,SMC2 |
| Mitotic Metaphase and Anaphase | CENPE,ZW10,LEMD3,RANGAP1B,KNTC1,NDC80,PDS5B,NUF2,CDCA8,VRK2 |
| Cell Cycle, Mitotic | MCPH1,APITD1,ITGB3BP,CENPJ,CEP135,NDE1,CENPI,CENPQ,NDEL1B,HAUS2 |
| M Phase | WAPAL,NCAPG,SKA2,SPC24,PANE1,ANKLE2,CLIP1,SETA,KIF2A,APITD1 |
| Lissencephaly gene (LIS1) in neuronal migration and development | MAP1B,NDEL1,DYNLT1,KATNA1,DCX,DAB1,VLDLR,LRPAP1 |
| Mitotic Anaphase | CENPE,CENPN,PMF1,CENPP,LEMD3,B9D2,CENPQ,ANKLE2,SPC24,ZWILCH |
| Mitotic Telophase/Cytokinesis | MAU2,NIPBLB,NIPBL,NIPBLA |
Protein Function
NUDC has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NUDC itself. We selected most functions NUDC had, and list some proteins which have the same functions with NUDC. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | DCX,MAP4K5,ZC3H10,MCC,NHP2L1,FAM127C,NUMBL,CDC42EP5,PARN,CCL20 |
Interacting Protein
NUDC has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NUDC here. Most of them are supplied by our site. Hope this information will be useful for your research of NUDC.
DNAJA2;FBXW2;WIPI2;gag-pol;WDR91;EML1;PEX7;GNB5;EIF1B;KIF21B;FBXO24;BAG2;MOS;ERBB2;RAG1
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References
- Meleady, P; Doolan, P; et al. Sustained productivity in recombinant Chinese Hamster Ovary (CHO) cell lines: proteome analysis of the molecular basis for a process-related phenotype. BMC BIOTECHNOLOGY 11:-(2011).
- Chuang, C; Lin, SH; et al. Acetylation of RNA Processing Proteins and Cell Cycle Proteins in Mitosis. JOURNAL OF PROTEOME RESEARCH 9:4554-4564(2010).
