NTSR1
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Official Full Name
neurotensin receptor 1 (high affinity) -
Overview
Neurotensin receptor 1 belongs to the large superfamily of G-protein coupled receptors. NTSR1 mediates the multiple functions of neurotensin, such as hypotension, hyperglycemia, hypothermia, antinociception, and regulation of intestinal motility and secretion. -
Synonyms
NTSR1;neurotensin receptor 1 (high affinity);neurotensin receptor type 1;NTR;High affinity levocabastine insensitive neurotensin receptor;NT R 1;NTR1;NTRH;NTRR;NTSR 1;NT-R-1;OTTHUMP00000031500;high-affinity levocabastine-insensitive neurotensin receptor
Recombinant Proteins
- Human
- Chicken
- Rat
- Mammalian Cell
- Wheat Germ
- HEK293
- E.coli expression system
- His
- Non
- Flag
- His&Flag
- Fc
- His&Fc&Avi
Involved Pathway
NTSR1 involved in several pathways and played different roles in them. We selected most pathways NTSR1 participated on our site, such as Calcium signaling pathway,Neuroactive ligand-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with NTSR1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Neuroactive ligand-receptor interaction | HTR2B,P2RY10,TAAR13B,GLRA2,GABRG1,C3AR1,GALR1,DRD2L,OXTR,NPY7R |
| Calcium signaling pathway | ORAI3,P2RX8,P2RX6,PTGER3,PRKACAB,PLCD3A,TNNC1A,PLCD1B,ATP2A1,PDE1A |
Protein Function
NTSR1 has several biochemical functions, for example, G-protein coupled neurotensin receptor activity,G-protein coupled receptor activity,protein N-terminus binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NTSR1 itself. We selected most functions NTSR1 had, and list some proteins which have the same functions with NTSR1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein homodimerization activity | TWIST1,SDCBP2,PDE2A,CHEK2,LMLN,PAFAH1B1,CDSN,PRTFDC1,Flt3l,CRYBB2 |
| protein N-terminus binding | RPA3,PDLIM5,MAP2K1,TRP53,KCNIP1,VWF,HDAC1,MECP2,EXOC4,PARP1 |
| G-protein coupled neurotensin receptor activity | NTSR2 |
| protein binding | B2M,CTTNBP2NL,RAB38,PIH1D3,HIST1H4H,PLP1,COL18A1,SRPK1,RXRG,ZNF238 |
| protein heterodimerization activity | NOTCH1,TCF3,PRMT5,TRP53,H3F3B,ZHX3,CHRNA5,ADIPOR1,H3F3A,HIST1H2AB |
| G-protein coupled receptor activity | GHSRA,OPN1SW1,OR12D2,CHRM5B,MRGPRF,TAAR14D,GPRC5B,TMTOPSA,SUCNR1,OR10W1 |
Interacting Protein
NTSR1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NTSR1 here. Most of them are supplied by our site. Hope this information will be useful for your research of NTSR1.
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