NT5M
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Official Full Name
5,3-nucleotidase, mitochondrial -
Overview
This gene encodes a 5 nucleotidase that localizes to the mitochondrial matrix. This enzyme dephosphorylates the 5-;and 2(3)-phosphates of uracil and thymine deoxyribonucleotides. The gene is located within the Smith-Magenis;syndrome region on chromosome 17. -
Synonyms
NT5M;5,3-nucleotidase, mitochondrial;5 nucleotidase, mitochondrial;5(3)-deoxyribonucleotidase, mitochondrial;dNT 2;dNT2;mdN;mitochondrial;3-nucleotidase;5;5(3)-deoxyribonucleotidase;Deoxy-5-nucleotidase 2;dNT-2;NT5M_HUMAN;OTTHUMP00000065515;mitochondrial 5 nucleotidase
Recombinant Proteins
- Mouse
- Rat
- Human
- E.coli
- Mammalian Cells
- Human
- HEK293
- His&T7
- His
- Non
- Myc&DDK
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Nt5m-1075M | Recombinant Mouse Nt5m protein, His & T7-tagged | E.coli | Mouse | His&T7 | Val30~His193 |
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| Nt5m-1076R | Recombinant Rat Nt5m protein, His & T7-tagged | E.coli | Rat | His&T7 | Val30~Arg209 |
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| NT5M-10931M | Recombinant Mouse NT5M Protein | Mammalian Cells | Mouse | His |
|
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| NT5M-1722H | Recombinant Human 5',3'-Nucleotidase, Mitochondrial, His-tagged | Human | Human | His |
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| NT5M-29347TH | Recombinant Human NT5M, His-tagged | E.coli | Human | His | 197 amino acids |
|
| NT5M-3673HCL | Recombinant Human NT5M 293 Cell Lysate | HEK293 | Human | Non |
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| NT5M-4489H | Recombinant Human NT5M Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293 | Human | Myc&DDK |
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| NT5M-5029H | Recombinant Human NT5M Protein (Val38-Cys228), N-His tagged | E.coli | Human | His | Val38-Cys228 |
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| NT5M-6231M | Recombinant Mouse NT5M Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| NT5M-6231M-B | Recombinant Mouse NT5M Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
NT5M involved in several pathways and played different roles in them. We selected most pathways NT5M participated on our site, such as Purine metabolism,Pyrimidine metabolism,Nicotinate and nicotinamide metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with NT5M were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolic pathways | HGSNAT,SAT2B,PAPSS2B,ALG3,MGAT1,ADH2-2,HMGCS2,FBP2,PLCD1A,CYP3A7-CYP3AP1 |
| Pyrimidine metabolism | CDA,POLR1A,NT5C2A,POLA2,POLE4,POLR2C,DHODH,POLR2F,ENTPD4,ENTPD5 |
| Nicotinate and nicotinamide metabolism | PNP,NADK2,NADSYN1,QPRT,NAPRT,NT5C1B-RDH14,NMRK2,NT5C2A,PNP5A,NMRK1 |
| Purine metabolism | POLR3GL,NT5C2B,PDE3A,POLR1C,PAPSS2B,POLR1D,POLR3F,AMPD3,PDE3B,AK4 |
Protein Function
NT5M has several biochemical functions, for example, 5-nucleotidase activity,metal ion binding,nucleotidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by NT5M itself. We selected most functions NT5M had, and list some proteins which have the same functions with NT5M. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| metal ion binding | HERC2,SCD5,ACVR2B,ZDHHC3B,MOCS3,SRSF7A,ITGA6,CA4B,ZNF317,LENG9 |
| 5-nucleotidase activity | NT5DC3,NT5C1AA,NT5C2A,NT5DC2,ACPP,NT5C3B,NT5C1BA,NT5C3A,NT5E,NT5C |
| nucleotide binding | RBPMS,GDPGP1,SYNCRIP,SAFB2,CAMKK1A,KALRN,ATP2B1,CLK4B,NONO,EPHA4B |
| nucleotidase activity | NT5C |
Interacting Protein
NT5M has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NT5M here. Most of them are supplied by our site. Hope this information will be useful for your research of NT5M.
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