NPHP1
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Official Full Name
nephronophthisis 1 (juvenile) homolog (human) -
Overview
Nephrocystin-1 is a protein that in humans is encoded by the NPHP1 gene. -
Synonyms
NPHP1;nephronophthisis 1 (juvenile) homolog (human);nephrocystin-1;JBTS4;Juvenile nephronophthisis 1 protein;Nephrocystin 1;NPH1;SLSN1
Recombinant Proteins
- Human
- Chicken
- Zebrafish
- E.coli
- Mammalian Cells
- Wheat Germ
- In Vitro Cell Free System
- GST
- His
- Non
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| NPHP1-3643H | Recombinant Human NPHP1 protein, GST-tagged | E.coli | Human | GST | 1-48 aa | |
| NPHP1-4301C | Recombinant Chicken NPHP1 | Mammalian Cells | Chicken | His |
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| NPHP1-4626Z | Recombinant Zebrafish NPHP1 | Mammalian Cells | Zebrafish | His |
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| NPHP1-1210HCL | Recombinant Human NPHP1 cell lysate | Human | Non |
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| NPHP1-6026H | Recombinant Human NPHP1 Protein, GST-tagged | Wheat Germ | Human | GST |
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| NPHP1-6620HF | Recombinant Full Length Human NPHP1 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 121 amino acids |
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| NPHP1-688H | Recombinant Human NPHP1 Protein (1-109 aa), GST-tagged | E.coli | Human | GST | 1-109 aa |
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Involved Pathway
NPHP1 involved in several pathways and played different roles in them. We selected most pathways NPHP1 participated on our site, such as Anchoring of the basal body to the plasma membrane,Assembly of the primary cilium,Organelle biogenesis and maintenance, which may be useful for your reference. Also, other proteins which involved in the same pathway with NPHP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Assembly of the primary cilium | IFT172,KIFAP3B,CNGA5,BBS5,DYF-1,HSPB11,TTC30A1,FLR,DYNLL2A,TTC30A2 |
| Organelle biogenesis and maintenance | TMEM216,MRPL48,MRPL49,ARL3,TTC30A2,MKKS,KIF3CB,MTRF1L,TTC30B,MRPL37 |
| Anchoring of the basal body to the plasma membrane | CSNK1D,MAPRE1A,IQCB1,TCTN1,CCDC41,SDCCAG8,DCTN2,CEP97,SSNA1,CEP152 |
Protein Function
NPHP1 has several biochemical functions, for example, protein binding,structural molecule activity. Some of the functions are cooperated with other proteins, some of the functions could acted by NPHP1 itself. We selected most functions NPHP1 had, and list some proteins which have the same functions with NPHP1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| structural molecule activity | KRT96,KRT18,KRT86,EPB41L3B,ASPH,CTNNA1,CLDNF,CLDN23,CLDN5B,CLDN15A |
| protein binding | FAM212A,CXCL2,LCA5,ZNF496,EHD2,BUD13,BARHL2,ADRB1,TSG101,ZFYVE1 |
Interacting Protein
NPHP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NPHP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of NPHP1.
PKD1;ADAM15;AHI1;ASAP1;K15-M;MED28;UBQLN4
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