NKX2-6
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Official Full Name
NK2 transcription factor related, locus 6 (Drosophila) -
Synonyms
NKX2-6;NK2 transcription factor related, locus 6 (Drosophila);homeobox protein Nkx-2.6;CSX2;homeobox protein NK2 homolog F;Homeobox protein Nkx2.6;NKX2F;NKX4 2;Tinman paralog;homeobox protein NK-2 homolog F;Drosophila NK2 transcription factor related, locus 6;Tix;Nkx2.6;tinman;Nkx-2.6;AV044928
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| NKX2-6-10701M | Recombinant Mouse NKX2-6 Protein | Mammalian Cells | Mouse | His |
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| NKX2-6-6694C | Recombinant Chicken NKX2-6 | Mammalian Cells | Chicken | His |
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| NKX2-6-3578H | Recombinant Human NKX2-6 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293 | Human | Myc&DDK |
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| Nkx2-6-4425M | Recombinant Mouse Nkx2-6 Protein, Myc/DDK-tagged | HEK293 | Mouse | Myc&DDK |
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| NKX2-6-6086M | Recombinant Mouse NKX2-6 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| NKX2-6-6086M-B | Recombinant Mouse NKX2-6 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
NKX2-6 involved in several pathways and played different roles in them. We selected most pathways NKX2-6 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with NKX2-6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
NKX2-6 has several biochemical functions, for example, DNA binding,sequence-specific DNA binding,transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NKX2-6 itself. We selected most functions NKX2-6 had, and list some proteins which have the same functions with NKX2-6. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| sequence-specific DNA binding | TP53,MNX2A,ZIC3,FOXI2,OSR2,PAX6A,LHX9,BARHL1B,NR2F6B,ESRRA |
| DNA binding | SSH2,HIST1H3H,ZIC5,NEUROD6A,ILF2,TRIM28,NPAS4A,TRAF4,ZNF596,NR4A2B |
| transcription factor activity, sequence-specific DNA binding | FOXO6,POU4F3,MLXIPL,TFEB,ZNF544,TADA2B,GPBP1L1,ZGPAT,ZFP770,LMO4 |
Interacting Protein
NKX2-6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NKX2-6 here. Most of them are supplied by our site. Hope this information will be useful for your research of NKX2-6.
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References
- Pereda, CM; Lesueur, F; et al. Common variants at the 9q22.33, 14q13.3 and ATM loci, and risk of differentiated thyroid cancer in the Cuban population. BMC GENETICS 16:-(2015).
- Wang, J; Zhang, DF; et al. NKX2-6 mutation predisposes to familial atrial fibrillation. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE 34:1581-1590(2014).
