NID1
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Official Full Name
nidogen 1 -
Overview
Entactin also known as nidogen-1 (NID-1) is a protein that in humans is encoded by the NID1 gene. Entactin is a component of the basement membrane alongside other components such as collagen type IV, proteoglycans (heparan sulfate and glycosaminoglycans), laminin and fibronectin. -
Synonyms
Nid1;nidogen1;NID;enactin1;NID-1;nidogen(enactin);entactin;nidogen-1;A630025O17;Nidogen precursor (Entactin);Nidogen;entactin;NID1;Ent;Entactin 1;NID 1;NID;Nidogen 1
Recombinant Proteins
- Human
- Mouse
- Hamster
- E.coli
- Mammalian cells
- HEK293
- Mammalian Cell
- Yeast
- Wheat Germ
- CHO
- Mamanlian cells
- His
- Myc&DDK
- GST
- Non
- Flag
- His&Fc&Avi
Involved Pathway
NID1 involved in several pathways and played different roles in them. We selected most pathways NID1 participated on our site, such as Degradation of the extracellular matrix,Extracellular matrix organization,Laminin interactions, which may be useful for your reference. Also, other proteins which involved in the same pathway with NID1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Laminin interactions | NID2,LAMC3,LAMB1B |
| Extracellular matrix organization | COL9A3,ADAM9,BGNA,LRP4,COL23A1,MGC174152,COL9A1A,FMOD,COL8A1,VCANB |
| Degradation of the extracellular matrix | CMA1,BSG,MMP12,CTSL2,COL17A1,CTSD,EMID2,CTSL1,KLK7,FURINB |
Protein Function
NID1 has several biochemical functions, for example, calcium ion binding,collagen binding,laminin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NID1 itself. We selected most functions NID1 had, and list some proteins which have the same functions with NID1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| laminin-1 binding | LACRT,Shh,UBE4A,NTN4,SLIT2,DAG1 |
| proteoglycan binding | COL5A1,CTSL1,FCN2,CECR1A,CTSB,SLIT2,CTSS,THBS1,CTSK,UBE4A |
| collagen binding | ITGA3,ADAM9,SERPINH1A,MTAP1A,CTSK,ASPN,SERPINH1,MMP9,PCOLCE,DDR1 |
| calcium ion binding | TMPRSS6,PVALB,GUCA1C,MEGF6,CPS1,EFHB,EFCAB5,F7,NECAB2,EGFL8 |
| laminin binding | LYPD5,ITGA3,CTSS,ACHE,LYPD3,LRRC15,ITGA9,PLEKHA2,LGALS2A,ITGB1 |
Interacting Protein
NID1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NID1 here. Most of them are supplied by our site. Hope this information will be useful for your research of NID1.
SKIL;p29991-pro_0000037946;dbpA;rfbD;q81va8_bacan;rne;mnmC;q99ib8-pro_0000045596;q9wmx2-pro_0000037548
Resources
Research Area
Epithelial Cell Markers and Intracellular MoleculesExtracellular Matrix Molecules
Other ECM Glycoproteins
Related Services
Related Products
References
- Li, L; Zhang, Y; et al. Nidogen-1: a candidate biomarker for ovarian serous cancer. JAPANESE JOURNAL OF CLINICAL ONCOLOGY 45:176-182(2015).
- Alazami, AM; Patel, N; et al. Accelerating Novel Candidate Gene Discovery in Neurogenetic Disorders via Whole-Exome Sequencing of Prescreened Multiplex Consanguineous Families. CELL REPORTS 10:148-161(2015).
