NGLY1
-
Official Full Name
N-glycanase 1 -
Synonyms
NGLY1;N-glycanase 1;17646;ENSG00000151092;PNG1;PNGase;3p24.2;FLJ11005, FLJ12409;peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase;peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase;hPNGase;peptide:N-glycanase;EC 3.5.1.52
Recombinant Proteins
- Human
- Mouse
- Chicken
- Zebrafish
- Rat
- Cynomolgus
- E.coli
- Mammalian Cells
- HEK293
- His
- Non
- Myc&DDK
- His&Fc&Avi
Involved Pathway
NGLY1 involved in several pathways and played different roles in them. We selected most pathways NGLY1 participated on our site, such as Protein processing in endoplasmic reticulum, which may be useful for your reference. Also, other proteins which involved in the same pathway with NGLY1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Protein processing in endoplasmic reticulum | UBE2D1A,DNAJC5,PDIA4,ERLEC1,STT3A,HSPH1,DNAJB1,UBE2D2A,DNAJB12A,UBQLN4 |
Protein Function
NGLY1 has several biochemical functions, for example, metal ion binding,peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NGLY1 itself. We selected most functions NGLY1 had, and list some proteins which have the same functions with NGLY1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| metal ion binding | ZNF302,LDB3A,TRIM108,HSPB11,ZFP74,KLF2A,S100S,CA5,RPE65B,CAR3 |
| protein binding | METAP2,GGA2,OS9,TRAPPC6A,SPTBN1,CWC22,A1CF,CRABP2,FGFR4,HMGB3 |
Interacting Protein
NGLY1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NGLY1 here. Most of them are supplied by our site. Hope this information will be useful for your research of NGLY1.
TRAFD1;RAD23A;RAD23B;UBXN2B;GUCD1;TRIM54
Resources
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References
- Kawabe, K; Tateyama, D; et al. A novel antibody for human induced pluripotent stem cells and embryonic stem cells recognizes a type of keratan sulfate lacking oversulfated structures. GLYCOBIOLOGY 23:322-336(2013).
- Singh, S; Verma, R; et al. Dynamic Ligand Modulation of EPO Receptor Pools, and Dysregulation by Polycythemia-Associated EPOR Alleles. PLOS ONE 7:-(2012).
