NGB

  • Official Full Name

    neuroglobin
  • Overview

    This gene encodes an oxygen-binding protein that is distantly related to members of the globin gene family. It is highly conserved among other vertebrates. It is expressed in the central and peripheral nervous system where it may be involved in increasing oxygen availability and providing protection under hypoxic/ischemic conditions.
  • Synonyms

    NGB;neuroglobin

Recombinant Proteins

  • Human
  • Mouse
  • Rhesus macaque
  • Chicken
  • Rat
  • Zebrafish
  • E.coli
  • Mammalian Cells
  • HEK293
  • His
  • Non
  • GST
  • DDK
  • Myc
  • Avi
  • Fc
  • SUMO
Cat.# Product name Source (Host) Species Tag Protein Length Price
NGB-3224H Recombinant Human NGB protein, His-tagged E.coli Human His 1-151 aa
NGB-127H Recombinant Human Neuroglobin E.coli Human Non
NGB-229H Recombinant Human NGB E.coli Human Non
NGB-2649H Recombinant Human NGB protein, His & GST-tagged E.coli Human GST&His Met1~Glu151
Ngb-2650M Recombinant Mouse Ngb protein, His-tagged E.coli Mouse His Met1~Glu151
NGB-3021R Recombinant Rhesus monkey NGB Protein, His-tagged Mammalian Cells Rhesus macaque His
NGB-3195C Recombinant Chicken NGB Mammalian Cells Chicken His
NGB-3980R Recombinant Rat NGB Protein Mammalian Cells Rat His
NGB-9358Z Recombinant Zebrafish NGB Mammalian Cells Zebrafish His
NGB-3837HCL Recombinant Human NGB 293 Cell Lysate HEK293 Human Non
NGB-1025H Recombinant Human NGB Protein, GST-tagged E.coli Human GST 1-151 a.a.
NGB-1854H Recombinant Human NGB Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293 Human DDK&Myc
NGB-2840R Recombinant Rhesus Macaque NGB Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque Avi&Fc&His
NGB-2840R-B Recombinant Rhesus Macaque NGB Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
NGB-3275H Recombinant Human NGB protein, His-SUMO-tagged E.coli Human His&SUMO 1-151aa
NGB-3639R Recombinant Rat NGB Protein, His (Fc)-Avi-tagged HEK293 Rat Avi&Fc&His
NGB-3639R-B Recombinant Rat NGB Protein Pre-coupled Magnetic Beads HEK293 Rat
Ngb-4404M Recombinant Mouse Ngb Protein, Myc/DDK-tagged HEK293 Mouse DDK&Myc
NGB-5050H Recombinant Human NGB Protein (Met1-Glu151), N-GST tagged E.coli Human GST Met1-Glu151

    Involved Pathway

    NGB involved in several pathways and played different roles in them. We selected most pathways NGB participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with NGB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    Protein Function

    NGB has several biochemical functions, for example, heme binding,metal ion binding,oxygen binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NGB itself. We selected most functions NGB had, and list some proteins which have the same functions with NGB. You can find most of the proteins on our site.

    Function Related Protein
    heme binding CYP17A2,CYP3C1L2,NOS1,CYP1A4,CYP2C18,HBB,PGRMC1,HBG2,CYP2J2,CYP1D1
    metal ion binding Gh,ZNF624,LMAN2L,XPA,CD209A,ZFP36,MMP14A,RPS6KAL,ZFP91,DNMT3A
    oxygen binding CYGB,HBG1,CYP2P9,CYP1A4,CYP2P10,HBG2,CYP2C37,CYP2C19,CYP17A1,CYP3A5
    protein binding KLK15,PYROXD1,SNX4,TOPORS,C11orf57,RSL24D1,GIMAP5,FAM46C,MAPK6,TUBA1A
    oxygen transporter activity HBM,HBBE2,CYGB1,HBB-Y,HBE1,BA1,HBQ1,HBBE1.1,CYGB,MB

    Interacting Protein

    NGB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NGB here. Most of them are supplied by our site. Hope this information will be useful for your research of NGB.

    TDO2;REL;VAC14;C1orf94;CCDC36;L3MBTL3

    Resources

    References

    • Lan, WB; Lin, JH; et al. Overexpressing neuroglobin improves functional recovery by inhibiting neuronal apoptosis after spinal cord injury. BRAIN RESEARCH 1562:100-108(2014).
    • Raida, Z; Hundahl, CA; et al. Neuroglobin Over Expressing Mice: Expression Pattern and Effect on Brain Ischemic Infarct Size. PLOS ONE 8:-(2013).

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