NEUROD6
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Official Full Name
neurogenic differentiation 6 -
Overview
NEUROD6 is a member of the NEUROD (NEUROD1; MIM 601724) family of basic helix-loop-helix (bHLH) transcription factors;(Guo et al., 2002 (PubMed 12357074)). -
Synonyms
NEUROD6;neurogenic differentiation 6;neurogenic differentiation factor 6;Atoh2;bHLHa2;Math 2;NEX1M;Atoh 2;Atonal homolog 2;Atonal protein homolog 2;Atonal protein homolog2;bHLH a2;bHLHa 2;Class A basic helix-loop-helix protein 2;Helix loop helix protein mATH 2;Helix loop helix protein mATH2;Math2;NDF 6;NDF6;NDF6_HUMAN;Neuro D6;Nex 1;Nex 1m;Nex;Nex1;Nex1 m;Protein atonal homolog 2;Protein atonal homolog2;OTTHUMP00000123444;Math-2
Recombinant Proteins
- Mouse
- Rhesus macaque
- Cynomolgus
- Human
- Mammalian Cells
- Tobacco (Nicotiana tabacum)
- E.coli
- Protein Conjugation
- HEK293
- Wheat Germ
- His
- Strep
- His&TRxA
- His&Fc&Avi
- GST
Involved Pathway
NEUROD6 involved in several pathways and played different roles in them. We selected most pathways NEUROD6 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with NEUROD6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
NEUROD6 has several biochemical functions, for example, DNA binding,RNA polymerase II core promoter proximal region sequence-specific DNA binding,protein dimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by NEUROD6 itself. We selected most functions NEUROD6 had, and list some proteins which have the same functions with NEUROD6. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding | TFE3A,NR5A2,AKNA,ESR1,SOX2,NOBOX,ONECUTL,MTF1,YBX1,PLAG1 |
| DNA binding | ATRX,RCAN1,HIST1H4E,ZKSCAN17,CXXC4,NHEJ1,ZNF45,FOXP2,MYCLA,PRRX1B |
| protein dimerization activity | DAO,SREBF2,MEF2D,SIM1,POU2F3,MESPBB,HER11,FBXW11B,PPP3CB,ASCL5 |
| RNA polymerase II core promoter proximal region sequence-specific DNA binding | RFX5,SMAD1,JUNBB,HLTF,NOBOX,PHOX2B,CUX2,CEBPZ,FIGLA,TBX3 |
Interacting Protein
NEUROD6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NEUROD6 here. Most of them are supplied by our site. Hope this information will be useful for your research of NEUROD6.
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References
- Katic, J; Loers, G; et al. Interaction of the Cell Adhesion Molecule CHL1 with Vitronectin, Integrins, and the Plasminogen Activator Inhibitor-2 Promotes CHL1-Induced Neurite Outgrowth and Neuronal Migration. JOURNAL OF NEUROSCIENCE 34:14606-14623(2014).
- Wang, XJ; Zhao, ZY; et al. Adipose stem cells-conditioned medium blocks 6-hydroxydopamine-induced neurotoxicity via the IGF-1/PI3K/AKT pathway. NEUROSCIENCE LETTERS 581:98-102(2014).
