NEDD9
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Official Full Name
neural precursor cell expressed, developmentally down-regulated 9 -
Overview
The protein encoded by this gene is a member of the CRK-associated substrates family. Members of this family are adhesion docking molecules that mediate protein-protein interactions for signal transduction pathways. This protein is a focal adhesion protein that acts as a scaffold to regulate signaling complexes important in cell attachment, migration and invasion as well as apoptosis and the cell cycle. This protein has also been reported to have a role in cancer metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012] -
Synonyms
NEDD9;neural precursor cell expressed, developmentally down-regulated 9;CAS2;CASL;HEF1;CAS-L;CASS2;enhancer of filamentation 1;cas-like docking;p130Cas-related protein;Enhancer of filamentation 1 p55;renal carcinoma antigen NY-REN-12;Cas scaffolding protein family member 2;Crk-associated substrate related protein Cas-L;neural precursor cell expressed developmentally down-regulated protein 9
Recombinant Proteins
- Human
- Mouse
- Zebrafish
- E. coli
- Mammalian Cell
- E.coli
- HEK293
- Wheat Germ
- HEK293T
- In Vitro Cell Free System
- Mammalian cells
- His
- Non
- His&Fc&Avi
- GST
- Myc&DDK
- Flag
Involved Pathway
NEDD9 involved in several pathways and played different roles in them. We selected most pathways NEDD9 participated on our site, such as B Cell Receptor Signaling Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with NEDD9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| B Cell Receptor Signaling Pathway | GSK3AB,PPP3CC,NFATC1,PLEKHA1,PDPK1A,PIK3AP1,STAP1,PIK3CA,NFATC3,CD19 |
Protein Function
NEDD9 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NEDD9 itself. We selected most functions NEDD9 had, and list some proteins which have the same functions with NEDD9. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | FCRL4,C1orf109,ZSCAN16,CEP104,CLDN2,YWHAE,PPFIA4,MUC7,FOXB1,ACAA1 |
Interacting Protein
NEDD9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NEDD9 here. Most of them are supplied by our site. Hope this information will be useful for your research of NEDD9.
TRIM27;NAB2;BANP;ITCH;BCAR3;NFKBIA
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