NDUFB11
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Official Full Name
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa -
Overview
NDUFB11 is a component of mitochondrial complex I. Complex I catalyzes the first step in the electron transport chain, the transfer of 2 electrons from NADH to ubiquinone, coupled to the translocation of 4 protons across the membrane (Carroll et al., 2002 (PubMed 12381726)). -
Synonyms
NDUFB11;NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa;NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial;complex I NP17.3 subunit;ESSS;Np15;NP17.3;CI ESSS;Complex I ESSS;FLJ20494;MGC111182;NADH dehydrogenase (ubiquinone) 1 beta subcomplex 11 17.3kDa;NADH dehydrogenase (ubiquinone) 1 beta subcomplex 11;NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11;NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11 mitochondrial;NADH ubiquinone oxidoreductase ESSS subunit;NDUFB 11;Neuronal protein 17.3;P17.3;CI-ESSS;complex I-ESSS;OTTHUMP00000023193;OTTHUMP00000023194;NADH-ubiquinone oxidoreductase ESSS subunit
Recombinant Proteins
- Human
- Zebrafish
- Bovine
- Pan troglodytes
- Gorilla gorilla gorilla (Western lowland gorilla)
- Mus musculus
- Pongo Pygmaeus
- Cricetulus griseus
- E.coli
- HEK293
- Mammalian Cells
- GST
- His
- Non
Involved Pathway
NDUFB11 involved in several pathways and played different roles in them. We selected most pathways NDUFB11 participated on our site, such as Oxidative phosphorylation,Metabolic pathways,Non-alcoholic fatty liver disease (NAFLD), which may be useful for your reference. Also, other proteins which involved in the same pathway with NDUFB11 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Parkinsons disease | SLC25A6,NDUFA4,GNAI3,NDUFV2,UBB,COX4I2,NDUFC2,NDUFB6,UQCR10,UQCRC2 |
| Huntingtons disease | NDUFA4,SOD2,DNAI2,NDUFB1,CASP9,POLR2E,NDUFA11,ATP5H,NDUFA12,ATP5O |
| Non-alcoholic fatty liver disease (NAFLD) | NDUFB8,NDUFAB1,NDUFA4L2,SDHB,BID,DDIT3,NDUFB3,UQCRFS1,NDUFA13,AKT2 |
| Metabolic pathways | CERS5,SDS,ITGB1BP3,NT5C2A,GALNT5,DGAT2,NSDHL,NT5C2,GALNT14,NME7 |
| Alzheimers disease | NDUFB3,COX7B2,ERN1,COX5A,CDK5R1,MME,NDUFA8,PPP3CA,LPL,UQCR10 |
| Oxidative phosphorylation | COX4I2,COX5B2,ATP5IA,ATP6V1F,UQCR10,ATP6V1C1A,NDUFB2,NDUFB7,COX7B2,ATP6V1G2 |
Protein Function
NDUFB11 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NDUFB11 itself. We selected most functions NDUFB11 had, and list some proteins which have the same functions with NDUFB11. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | UQCRH,GADD45A,ZNHIT6,NSMCE1,ZNF224,ITGA6,PRKDC,HIST1H3C,STAR,SRSF2 |
Interacting Protein
NDUFB11 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NDUFB11 here. Most of them are supplied by our site. Hope this information will be useful for your research of NDUFB11.
FATE1;NDUFA2;PPBP;CRELD2;NDUFS5;NDUFS3;Mtx2;Rab5c;RAB5C;NDUFA6;Atp5a1;NDUFA9;Sass6;NDUFA11;Tnpo1;ECSIT;VAPA
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References
- Al-Quraishy, S; Dkhil, MA; et al. Genome-wide screening identifies Plasmodium chabaudi-induced modifications of DNA methylation status of Tlr1 and Tlr6 gene promoters in liver, but not spleen, of female C57BL/6 mice. PARASITOLOGY RESEARCH 112:3757-3770(2013).
- Lorusso, FP; et al. Alternative splicing of the X-linked NDUFB11 gene and its implication in mitochondrial complex I function and apoptotic process. FEBS JOURNAL 280:35-35(2013).
