NAT8B
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Official Full Name
N-acetyltransferase 8B (GCN5-related, putative, gene/pseudogene) -
Overview
The protein encoded by this gene is highly similar to the N-acetyltransferase 8 (NAT8) gene product, which is a kidney and liver protein with homology to bacterial acetyltransferases involved in drug resistance. This gene is localized on chromosome 2 in the vicinity of the NAT8 gene and may represent a pseudogene of NAT8. This gene contains two polymorphic nonsense mutations that disrupt the active site of the protein. The full-length product of this gene contains a complete acetyltransferase domain and is identical in length to NAT8. -
Synonyms
NAT8B;N-acetyltransferase 8B (GCN5-related, putative, gene/pseudogene);N acetyltransferase 8B (gene/pseudogene);probable N-acetyltransferase 8B;Hcml2;NAT8BP;Camello like protein 2;Camello-like protein 2;CML2;N acetyltransferase 8B;NAT8B_HUMAN;Probable N acetyltransferase 8B;N-acetyltransferase Camello 2;N-acetyltransferase 8B (gene/pseudogene)
Recombinant Proteins
- Human
- Rat
- Chicken
- Wheat Germ
- Mammalian Cell
- HEK293
- HEK293T
- E.coli expression system
- GST
- His
- Non
- Myc&DDK
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| NAT8B-1540H | Recombinant Human NAT8B Protein, GST-tagged | Wheat Germ | Human | GST |
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| NAT8B-3909R | Recombinant Rat NAT8B Protein | Mammalian Cell | Rat | His |
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| NAT8B-4660C | Recombinant Chicken NAT8B | Mammalian Cell | Chicken | His |
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| NAT8B-3961HCL | Recombinant Human NAT8B 293 Cell Lysate | HEK293 | Human | Non |
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| NAT8B-3302H | Recombinant Human NAT8B Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| NAT8B-3568R | Recombinant Rat NAT8B Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| NAT8B-3568R-B | Recombinant Rat NAT8B Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| RFL27433HF | Recombinant Full Length Human Probable N-Acetyltransferase 8B(Nat8B) Protein, His-Tagged | E.coli expression system | Human | His | Full L. Full Length (1-227) |
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Involved Pathway
NAT8B involved in several pathways and played different roles in them. We selected most pathways NAT8B participated on our site, such as Amyloid formation,Metabolism of proteins,metapathway biotransformation, which may be useful for your reference. Also, other proteins which involved in the same pathway with NAT8B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Amyloid formation | ODAM,SAA1,CST3,TGFBI,HIST3H2BB,LTF,SEMG1,CEACAM21,HIST4H4,RHBDL1 |
| metapathway biotransformation | PRKRA,CYP4Z1,CYP20A1,NAA50,CHST4,KCNAB1,NAT8,GAL3ST4,RHBDL1,SULT4A1 |
| Metabolism of proteins | GFER,NSMCE4A,SPON1,IGF2B,MUCL1,TIMM22,ARSI,CGB5,TIMM21,GAS6 |
Protein Function
NAT8B has several biochemical functions, for example, N-acetyltransferase activity,lysine N-acetyltransferase activity, acting on acetyl phosphate as donor,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NAT8B itself. We selected most functions NAT8B had, and list some proteins which have the same functions with NAT8B. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| N-acetyltransferase activity | CML2,NAT9,SAT2A,SAT1A.1,SAT1A.2,SMARCE1,LPCAT3,MBOAT4,ACNAT2,MBOAT1 |
| protein binding | HBA1,LRRC33,TNFSF12,SPRR2A,RNF220,DNAJC28,ICAM4,TACC1,PRLR,GOSR2 |
| lysine N-acetyltransferase activity, acting on acetyl phosphate as donor | ESCO2,RHBDL1,CEACAM21,NAT8,EP300,KAT2B |
Interacting Protein
NAT8B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NAT8B here. Most of them are supplied by our site. Hope this information will be useful for your research of NAT8B.
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