NACC1
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Official Full Name
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing -
Overview
This gene encodes a member of the BTB/POZ protein family. BTB/POZ proteins are involved in several cellular processes;including proliferation, apoptosis and transcription regulation. The encoded protein is a transcriptional repressor;that plays a role in stem cell self-renewal and pluripotency maintenance. The encoded protein also suppresses;transcription of the candidate tumor suppressor Gadd45GIP1, and expression of this gene may play a role in the;progression of multiple types of cancer. A pseudogene of this gene is located on the short arm of chromosome 9. -
Synonyms
NACC1;nucleus accumbens associated 1, BEN and BTB (POZ) domain containing;BTB (POZ) domain containing 14B , BTBD14B;nucleus accumbens-associated protein 1;BEN domain containing 8;BEND8;NAC 1;NAC1;nucleus accumbens associated 1;transcriptional rep
Recombinant Proteins
- Human
- Mouse
- Rat
- E.coli
- Mammalian Cells
- HEK293
- GST
- His
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| NACC1-1168H | Recombinant Human NACC1 protein, GST-tagged | E.coli | Human | GST | 173-527 aa | |
| NACC1-1169H | Recombinant Human NACC1 protein, His-tagged | E.coli | Human | His | 173-527 aa | |
| NACC1-10398M | Recombinant Mouse NACC1 Protein | Mammalian Cells | Mouse | His |
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| NACC1-3886R | Recombinant Rat NACC1 Protein | Mammalian Cells | Rat | His |
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| NACC1-3545R | Recombinant Rat NACC1 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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| NACC1-3545R-B | Recombinant Rat NACC1 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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| NACC1-5892M | Recombinant Mouse NACC1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| NACC1-5892M-B | Recombinant Mouse NACC1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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Involved Pathway
NACC1 involved in several pathways and played different roles in them. We selected most pathways NACC1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with NACC1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
NACC1 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by NACC1 itself. We selected most functions NACC1 had, and list some proteins which have the same functions with NACC1. You can find most of the proteins on our site.
| Function | Related Protein |
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Interacting Protein
NACC1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NACC1 here. Most of them are supplied by our site. Hope this information will be useful for your research of NACC1.
STRN3;SNW1;CDC5L;MAP3K5
Resources
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References
- Gao, M; Wu, RC; et al. Identification of the NAC1-Regulated Genes in Ovarian Cancer. AMERICAN JOURNAL OF PATHOLOGY 184:133-140(2014).
- Yap, KL; Sysa-Shah, P; et al. Loss of NAC1 Expression Is Associated with Defective Bony Patterning in the Murine Vertebral Axis. PLOS ONE 8:-(2013).
