MYL6B
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Official Full Name
myosin, light chain 6B, alkali, smooth muscle and non-muscle -
Overview
Myosin is a hexameric ATPase cellular motor protein. It is composed of two heavy chains, two nonphosphorylatable alkali light chains, and two phosphorylatable regulatory light chains. This gene encodes a myosin alkali light chain expressed in both slow-twitch skeletal muscle and in nonmuscle tissue. Alternative splicing results in multiple transcript variants. -
Synonyms
MYL6B;myosin, light chain 6B, alkali, smooth muscle and non-muscle;myosin, light polypeptide 6B, alkali, smooth muscle and non muscle;myosin light chain 6B;MLC1SA;myosin light chain 1 slow a;MYL 6B;MYL6B_HUMAN;Myosin alkali light chain 1 slow a;Myosin light chain 1 slow twitch muscle A isoform;Myosin light chain 1 slow-twitch muscle A isoform;Myosin light chain 6B alkali smooth muscle and non muscle;Myosin light polypeptide 6B alkali smooth muscle and non muscle;Myosin light polypeptide 6B;Smooth muscle and non muscle myosin alkali light chain 6B;Smooth muscle and nonmuscle myosin light chain alkali 6B;OTTHUMP00000243208;OTTHUMP00000243210;OTTHUMP00000243299;myosin light chain 1, slow-twitch muscle A isoform;smooth muscl
Recombinant Proteins
- Mouse
- Rhesus macaque
- Human
- Rat
- Mammalian Cells
- E.coli
- Human
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- His
- His&GST
- Non
- His&Fc&Avi
- Myc&DDK
- GST
Involved Pathway
MYL6B involved in several pathways and played different roles in them. We selected most pathways MYL6B participated on our site, such as Muscle contraction,Oxytocin signaling pathway,Smooth Muscle Contraction, which may be useful for your reference. Also, other proteins which involved in the same pathway with MYL6B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Smooth Muscle Contraction | LMOD1,SORBS3 |
| Muscle contraction | TNNI2A.4,TNNI1B,TMEM8C,TNNI2,TMOD3,MYL1,TRIM72,TNNT3B,MYBPC2,TNNT3A |
| Oxytocin signaling pathway | ROCK1,PRKAB1,CACNB4,ITPR1,CAMK2D,PRKAA1,GNAO1,PRKAA2,CAMK1G,FOS |
| Vascular smooth muscle contraction | GNA11B,PLCB1,PRKACAB,ADCY2B,ITPR1,PLCB2,CALM1,CACNA1SA,PPP1CC,CYP4A10 |
Protein Function
MYL6B has several biochemical functions, for example, calcium ion binding,motor activity,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MYL6B itself. We selected most functions MYL6B had, and list some proteins which have the same functions with MYL6B. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | XPO5,PHF15,F11R,IRF5,MMP9,FAM69A,GADD45G,DUSP15,MRPS23,SIRT4 |
| structural constituent of muscle | MYBPC3,SYNM,COX4I2,PDLIM3,MYL1,MYL3,MYL2,JPH1,MYOM1,SMTN |
| calcium ion binding | PCDHGC4,DAG1,CDH18A,ACTN1,ENPP1,THBS4B,PADI2,SYT5,ITSN2B,MMP13A |
| motor activity | KIF1C,DYNC1I1,MYO1G,MYH1E,MYHZ2,DYNLT1,MYH4,KIF2A,DNAHC8,MYO6B |
Interacting Protein
MYL6B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MYL6B here. Most of them are supplied by our site. Hope this information will be useful for your research of MYL6B.
SPA17;1-phosphatidyl-1d-myo-inositol 3,5-bisphosphate;1-phosphatidyl-1d-myo-inositol 4,5-bisphosphate;MYO5A;USP46;RIPK3;ESR1;NSS;MYH9;IQGAP1;CAPZA2;Actb;Myl12b
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