MYF6
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Official Full Name
myogenic factor 6 (herculin) -
Overview
The protein encoded by this gene is a probable basic helix-loop-helix (bHLH) DNA binding protein involved in muscle differentiation. The encoded protein likely acts as a heterodimer with another bHLH protein. Defects in this gene are a cause of autosomal dominant centronuclear myopathy (ADCNM). -
Synonyms
MYF6;myogenic factor 6 (herculin);myogenic factor 6;bHLHc4;MRF4;Class C basic helix-loop-helix protein 4;HERCULIN;Muscle-specific regulatory factor 4;Myf-6;MYF6_HUMAN;OTTHUMP00000243109
Recombinant Proteins
- Mouse
- Zebrafish
- Chicken
- Human
- Rat
- Mammalian Cells
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- His
- Non
- His&Fc&Avi
- GST
Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
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MYF6-10297M | Recombinant Mouse MYF6 Protein | Mammalian Cells | Mouse | His |
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MYF6-1181Z | Recombinant Zebrafish MYF6 | Mammalian Cells | Zebrafish | His |
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MYF6-2447C | Recombinant Chicken MYF6 | Mammalian Cells | Chicken | His |
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MYF6-29361TH | Recombinant Human MYF6 | Wheat Germ | Human | Non | 99 amino acids |
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MYF6-3844R | Recombinant Rat MYF6 Protein | Mammalian Cells | Rat | His |
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MYF6-4033HCL | Recombinant Human MYF6 293 Cell Lysate | HEK293 | Human | Non |
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MYF6-3503R | Recombinant Rat MYF6 Protein, His (Fc)-Avi-tagged | HEK293 | Rat | His&Fc&Avi |
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MYF6-3503R-B | Recombinant Rat MYF6 Protein Pre-coupled Magnetic Beads | HEK293 | Rat |
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MYF6-5801H | Recombinant Human MYF6 Protein, GST-tagged | Wheat Germ | Human | GST |
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MYF6-5836M | Recombinant Mouse MYF6 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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MYF6-5836M-B | Recombinant Mouse MYF6 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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MYF6-6741HF | Recombinant Full Length Human MYF6 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 242 amino acids |
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Involved Pathway
MYF6 involved in several pathways and played different roles in them. We selected most pathways MYF6 participated on our site, such as C-MYB transcription factor network,CDO in myogenesis,Developmental Biology, which may be useful for your reference. Also, other proteins which involved in the same pathway with MYF6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Developmental Biology | AP2M1,CNTN6,SPRED3,MYL9,ARPC1A,DNM1,ITGB3A,FGF18B,EFNA1A,MED29 |
CDO in myogenesis | SPAG9,BOC,MYOD1,CTNNA2,BNIP2,CTNNA1,CDON,TCF12,MEF2AA,CDH2 |
Myogenesis | SPAG9,TCF3B,MEF2AA,CDH4,CDON,TCF3A,TCF12,BNIP2,MYOD1,TCF4 |
Diurnally regulated genes with circadian orthologs | STBD1,ITM2B,DAZAP2,KLF9,EIF4G2,NR1D2,CEBPB,RBPMS,AZIN1,NCKAP1 |
C-MYB transcription factor network | ADORA2B,ELANE,CDKN1B,COL1A2,PRTN3,PIAS3,MYOD1,GATA1,YEATS4,MYB |
Id Signaling Pathway | MYOD1,TCF12,ACVRL1,MYOG,IFI16,ELK3,MSC,TCF3B,PAX2,KDR |
Protein Function
MYF6 has several biochemical functions, for example, contributes_to E-box binding,RNA polymerase II core promoter proximal region sequence-specific DNA binding,protein heterodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MYF6 itself. We selected most functions MYF6 had, and list some proteins which have the same functions with MYF6. You can find most of the proteins on our site.
Function | Related Protein |
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RNA polymerase II core promoter proximal region sequence-specific DNA binding | SFPI1,ZSCAN21,HOXA7,CEBPG,TCF3A,PITX2,KLF17,HOXA2,JUNBA,MITF |
transcription factor activity, sequence-specific DNA binding | ARNTL1B,CEBPD,LHX1A,MAFBA,MYRFL,GPBP1L1,TCF7,NFE2L2,CBFA2T3,PBX1B |
protein heterodimerization activity | TENM3,UBXN6,ABCG8,ERBB2,HIST1H4I,CLCF1,AGTR1A,OSTB,TCF4,PML |
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding | RFX1,POU3F1,SRY,ATF1,GLI1,FOXC1,POU3F3,SFPI1,MYOD1,JUN |
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding | LEF1,TRP53,RXRB,MAFA,BARHL2,ALX4,GATA5,REST,NKX2,GATA1A |
contributes_to E-box binding | MYF5,TCF3 |
Interacting Protein
MYF6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MYF6 here. Most of them are supplied by our site. Hope this information will be useful for your research of MYF6.
LAMTOR5;TCF12
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