MUC7
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Official Full Name
mucin 7, secreted -
Overview
This gene encodes a small salivary mucin, which is thought to play a role in facilitating the clearance of bacteria in the oral cavity and to aid in mastication, speech, and swallowing. The central domain of this glycoprotein contains tandem repeats, each composed of 23 amino acids. The most common allele contains 6 repeats, and some alleles may be associated with susceptibility to asthma. Alternatively spliced transcript variants with different 5 UTR, but encoding the same protein, have been found for this gene. -
Synonyms
MUC7;mucin 7, secreted;mucin 7, salivary;mucin-7;FLJ27047;MG2;DKFZp686J03256;Apo MG2;Apo-MG2;MGC34772;MUC 7;MUC-7;MUC7_HUMAN;Mucin 7;Salivary mucin 7;Salivary mucin-7;OTTHUMP00000160365;OTTHUMP00000219138
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| MUC7-3644H | Recombinant Human MUC7 protein, GST-tagged | E.coli | Human | GST | 22-95 aa | |
| MUC7-28540TH | Recombinant Human MUC7 | E.coli | Human | Non |
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| MUC7-1806H | Recombinant Human MUC7 Protein, His&GST-tagged | E.coli | Human | GST&His | Arg23-Gln377 |
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| MUC7-4644H | Recombinant Human MUC7 protein, His-PDI-tagged | Yeast | Human | His&PDI | 23-377aa |
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| MUC7-5751H | Recombinant Human MUC7 Protein, GST-tagged | Wheat Germ | Human | GST |
|
Involved Pathway
MUC7 involved in several pathways and played different roles in them. We selected most pathways MUC7 participated on our site, such as Salivary secretion, which may be useful for your reference. Also, other proteins which involved in the same pathway with MUC7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Salivary secretion | Slc4a2,LYZ,GNAS,PRKACA,BEST2,ITPR1,ATP1B2,CALM1,AQP5,BST1 |
Protein Function
MUC7 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MUC7 itself. We selected most functions MUC7 had, and list some proteins which have the same functions with MUC7. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | MMP15,FSCN1,DYNAP,NFKBIA,ATP2C2,PELI2,C19orf46,PPP3CA,ADAM33,DOK3 |
Interacting Protein
MUC7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MUC7 here. Most of them are supplied by our site. Hope this information will be useful for your research of MUC7.
STATH;PRH1;AMY1B;HTN1;HTN3;LAMA5;SMR3B;PRDX3;PFN2;PRR4
Resources
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References
- Takehara, S; Yanagishita, M; et al. Degradation of MUC7 and MUC5B in Human Saliva. PLOS ONE 8:-(2013).
- Soares, RV; Offner, GD; et al. An unusual glycoform of human salivary mucin MG2. CLINICAL ORAL INVESTIGATIONS 16:761-766(2012).
