MTMR1
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Official Full Name
myotubularin related protein 1 -
Overview
This gene encodes a member of the myotubularin related family of proteins. Members of this family contain the consensus sequence for the active site of protein tyrosine phosphatases. Alternatively spliced variants have been described but their biological validity has not been determined. -
Synonyms
MTMR1;myotubularin related protein 1;myotubularin-related protein 1;MTMR 1;Myotubularin related 1;OTTHUMP00000025855;OTTHUMP00000025856;OTTHUMP00000025864;OTTHUMP00000233786
Recombinant Proteins
- Mouse
- Human
- Mammalian Cell
- HEK293
- HEK293T
- Wheat Germ
- In Vitro Cell Free System
- His
- Non
- Myc&DDK
- GST
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| MTMR1-10201M | Recombinant Mouse MTMR1 Protein | Mammalian Cell | Mouse | His |
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| MTMR1-1147HCL | Recombinant Human MTMR1 cell lysate | Human | Non |
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| MTMR1-2192H | Recombinant Human MTMR1 Protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
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| Mtmr1-4214M | Recombinant Mouse Mtmr1 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| MTMR1-5711H | Recombinant Human MTMR1 Protein, GST-tagged | Wheat Germ | Human | GST |
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| MTMR1-5784M | Recombinant Mouse MTMR1 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| MTMR1-5784M-B | Recombinant Mouse MTMR1 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| MTMR1-6079H | Recombinant Human MTMR1 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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| MTMR1-6533HF | Recombinant Full Length Human MTMR1 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 38 amino acids |
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Involved Pathway
MTMR1 involved in several pathways and played different roles in them. We selected most pathways MTMR1 participated on our site, such as Inositol phosphate metabolism,Metabolic pathways,Phosphatidylinositol signaling system, which may be useful for your reference. Also, other proteins which involved in the same pathway with MTMR1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolic pathways | ADH1,PLA2G3,MAOA,GRHPR,RIMKLA,IL4I1,MAT2AB,FUT3,NSDHL,CYP3A41B |
| Inositol phosphate metabolism | PIP5K2,PIK3C3,INPP5J,PIP5K1BB,INPP5E,INPP5A,PIP4K2AA,SYNJ2,PI4K2B,INPP1 |
| Phosphatidylinositol signaling system | PPIP5K1,INPP5J,PIK3CD,OCRL,PLCB2,PIK3R1,IMPAD1,PI4KB,CALML3,CALM3B |
Protein Function
MTMR1 has several biochemical functions, for example, phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity,phosphatidylinositol-3-phosphatase activity,protein tyrosine phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by MTMR1 itself. We selected most functions MTMR1 had, and list some proteins which have the same functions with MTMR1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| phosphatidylinositol-3-phosphatase activity | MTMR1B,MTMR1A,FIG4,MTMR8,MTMR14,MTM1,SACM1L,MTMR3,MTMR2,PTEN |
| phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity | MTM1,MTMR1A,PTPRQ,MTMR8,SACM1LA,SGPP2,MTMR2,TENC1,MTMR3,NT5DC3 |
| protein tyrosine phosphatase activity | CDC14AA,DUSP16,CDC14A,PTPRR,DUSP12,DUSP22B,PTPN4B,DUSP11,DUSP14,PTPN4A |
Interacting Protein
MTMR1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MTMR1 here. Most of them are supplied by our site. Hope this information will be useful for your research of MTMR1.
Resources
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References
- Lee, JU; Son, JY; et al. Crystallization and preliminary X-ray crystallographic analysis of the PH-GRAM domain of human MTMR4. ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS 70:1280-1283(2014).
- Mohan, M; Chandra, LC; et al. miR-190b Is Markedly Upregulated in the Intestine in Response to Simian Immunodeficiency Virus Replication and Partly Regulates Myotubularin-Related Protein-6 Expression. JOURNAL OF IMMUNOLOGY 193:1301-1313(2014).
