MT3
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Official Full Name
metallothionein 3 -
Overview
Metallothionein-3 is a protein that in humans is encoded by the MT3 gene. -
Synonyms
MT3;metallothionein 3;metallothionein 3 (growth inhibitory factor (neurotrophic));metallothionein-3;GIF;GIFB;GRIF;Metallothionein III;Growth inhibitory factor;Metallothionein-III;Mt 3;MT III;MT-3;MT-III;MT3_HUMAN;OTTHUMP00000164383
Recombinant Proteins
- Mouse
- Human
- Rhesus macaque
- Chicken
- Rat
- Mammalian Cells
- Wheat Germ
- E.coli
- HEK293
- In Vitro Cell Free System
- His
- GST
- Non
- His&T7
- His&Fc&Avi
- His&SUMO
- His&Myc
Involved Pathway
MT3 involved in several pathways and played different roles in them. We selected most pathways MT3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with MT3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Protein Function
MT3 has several biochemical functions, for example, antioxidant activity,cadmium ion binding,copper ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MT3 itself. We selected most functions MT3 had, and list some proteins which have the same functions with MT3. You can find most of the proteins on our site.
Function | Related Protein |
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protein binding | SLC22A3,PIK3CG,NUDT18,JAKMIP1,STMN2,TUBB2B,BTG3,CCL18,BBS2,POGZ |
cysteine-type endopeptidase inhibitor activity involved in apoptotic process | AVP,LEF1,PRDX3,NAIP1,BIRC3,XIAP,TFAP2B,ARRB1,IGF1RB,CD27 |
antioxidant activity | KDM3B,S100A9,FAM213AA,TRP53INP1,CAT,TP53INP1,APOA4,SELS,UBIAD1,PRDX2 |
copper ion binding | F8,LOXL3,METTL17,RNF7,TYRP1,HEPHL1A,PARK7,TP53,PAM,LOX |
protein kinase activator activity | NKX3-1,STK11,FAM58A,NKX3,STRADA,CAB39,AGAP2,DAXX,PRKAG2,MAPK8IP2 |
zinc ion binding | LTN1,RBM5,RARAB,ZNF8,TRIM35-1,NEIL1,RBM4.1,ALPP,AIRE,TRAF2 |
cadmium ion binding | NOS1,P2RX2,NOS3,SLC11A2 |
drug binding | HMGB2,CHRNB2,FNTB,HTR2C,CHRNA7,CNR1,FSCN1,PDE2A,FASN,PPARD |
Interacting Protein
MT3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MT3 here. Most of them are supplied by our site. Hope this information will be useful for your research of MT3.
TTR;TERF2IP
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References
- Farhat, YM; Al-Maliki, AA; et al. Gene Expression Analysis of the Pleiotropic Effects of TGF-beta 1 in an In Vitro Model of Flexor Tendon Healing. PLOS ONE 7:-(2012).
- Alvarez, L; Gonzalez-Iglesias, H; et al. The Stoichiometric Transition from Zn6Cu1-Metallothionein to Zn-7-Metallothionein Underlies the Up-regulation of Metallothionein (MT) Expression QUANTITATIVE ANALYSIS OF MT-METAL LOAD IN EYE CELLS. JOURNAL OF BIOLOGICAL CHEMISTRY 287:28456-28469(2012).