MSL2

  • Official Full Name

    male-specific lethal 2 homolog
  • Synonyms

    MSL2;male-specific lethal 2 homolog (Drosophila);male specific lethal 2 like 1 (Drosophila) , MSL2L1, ring finger protein 184 , RNF184;male-specific lethal 2 homolog;FLJ10546;KIAA1585;male specific lethal 2 homolog (Drosophila);msl 2;MSL2-like 1

Recombinant Proteins

  • Mouse
  • Rhesus macaque
  • Human
  • Arabidopsis thaliana
  • Mammalian Cells
  • E.coli
  • HEK293
  • Wheat Germ
  • In Vitro Cell Free System
  • His
  • Non
  • Avi&Fc&His
  • GST
Cat.# Product name Source (Host) Species Tag Protein Length Price
MSL2-10138M Recombinant Mouse MSL2 Protein Mammalian Cells Mouse His
MSL2-2874R Recombinant Rhesus monkey MSL2 Protein, His-tagged Mammalian Cells Rhesus macaque His
MSL2-83H Recombinant Human MSL2, His-tagged E.coli Human His
MSL2-4114HCL Recombinant Human MSL2 293 Cell Lysate HEK293 Human Non
MSL2-2694R Recombinant Rhesus Macaque MSL2 Protein, His (Fc)-Avi-tagged HEK293 Rhesus macaque Avi&Fc&His
MSL2-2694R-B Recombinant Rhesus Macaque MSL2 Protein Pre-coupled Magnetic Beads HEK293 Rhesus macaque
MSL2-5656H Recombinant Human MSL2 Protein, GST-tagged Wheat Germ Human GST
MSL2-5743M Recombinant Mouse MSL2 Protein, His (Fc)-Avi-tagged HEK293 Mouse Avi&Fc&His
MSL2-5743M-B Recombinant Mouse MSL2 Protein Pre-coupled Magnetic Beads HEK293 Mouse
MSL2-6459HF Recombinant Full Length Human MSL2 Protein, GST-tagged In Vitro Cell Free System Human GST Full L. 577 amino acids
RFL34101AF Recombinant Full Length Arabidopsis Thaliana Mechanosensitive Ion Channel Protein 2, Chloroplastic(Msl2) Protein, His-Tagged E.coli Arabidopsis thaliana His Full L. Full Length of Mature Protein (76-673)

    Involved Pathway

    MSL2 involved in several pathways and played different roles in them. We selected most pathways MSL2 participated on our site, such as Chromatin modifying enzymes,Chromatin organization,HATs acetylate histones, which may be useful for your reference. Also, other proteins which involved in the same pathway with MSL2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Chromatin organization MTA1,PBRM1L,MSL1A,MSL1,VPS72,JHDM1D,KAT6A,PHF15,KANSL3,KDM7AB
    HATs acetylate histones CSRP2BP,PAX3A,BRPF3,TADA2A,SAP130,MSL2B,JADE1,ANO9A,KANSL3,EP400
    Chromatin modifying enzymes WDR77,PADI3,MCRS1,SMARCA4,BRPF1,ING5,PADI4,ZZZ3,KDM4A,KAT8

    Protein Function

    MSL2 has several biochemical functions, for example, ligase activity,ubiquitin protein ligase activity,zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MSL2 itself. We selected most functions MSL2 had, and list some proteins which have the same functions with MSL2. You can find most of the proteins on our site.

    Function Related Protein
    ligase activity PRPF19,UHRF2,TRIM2,RNF216,RNF138,RNF169,UBE2KA,MKRN3,UBE2D1B,RLIM
    ubiquitin protein ligase activity HECTD1,ZNRF2,ANKIB1,RNF13,LTN1,MARCH8,BFAR,MSL2B,RNF144A,FLJ11011L
    zinc ion binding CPM,CPN1,TRAF4B,NRD1B,PDZRN3B,NR5A2,ZCCHC10,ABLIM1B,MICALL2A,CA13

    Interacting Protein

    MSL2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MSL2 here. Most of them are supplied by our site. Hope this information will be useful for your research of MSL2.

    Kat8;YWHAG;YWHAE;q7ckv2_yerpe;aacA-aphD;TRIM8;WNK1;Mis12

    Resources

    References

    • Sugimoto, TN; Fujii, T; et al. Expression of a doublesex homologue is altered in sexual mosaics of Ostrinia scapulalis moths infected with Wolbachia. INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY 40:847-854(2010).
    • Abaza, I; Coll, O; et al. Drosophila UNR is required for translational repression of male-specific lethal 2 mRNA during regulation of X-chromosome dosage compensation. GENES & DEVELOPMENT 20:380-389(2006).

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