MS4A3
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Official Full Name
membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) -
Overview
This gene encodes a member of the membrane-spanning 4A gene family. Members of this protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. This family member likely plays a role in signal transduction and may function as a subunit associated with receptor complexes. The gene encoding this protein is localized to 11q12, among a cluster of related family members. Alternative splicing may result in multiple transcript variants; however, not all variants have been fully described. -
Synonyms
MS4A3;membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific);CD20L;membrane-spanning 4-domains subfamily A member 3;HTM4;CD20 antigen homolog;CD20 antigen like;CD20 antigen like protein;hematopoietic cell 4 transmembrane protein;Hematopoietic-specific transmembrane protein 4;IgE receptor beta subunit;OTTHUMP00000235850;OTTHUMP00000235851;OTTHUMP00000235853;IgE receptor beta chain;CD20 antigen-like protein
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| MS4A3-1049H | Recombinant Human MS4A3, His-tagged | E.coli | Human | His | 1-214aa | |
| MS4A3-4125HCL | Recombinant Human MS4A3 293 Cell Lysate | HEK293 | Human | Non |
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| MS4A3-5636H | Recombinant Human MS4A3 Protein, GST-tagged | Wheat Germ | Human | GST |
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| MS4A3-6541HF | Recombinant Full Length Human MS4A3 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 214 amino acids |
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| RFL13181HF | Recombinant Full Length Human Membrane-Spanning 4-Domains Subfamily A Member 3(Ms4A3) Protein, His-Tagged | E.coli | Human | His | Full L. Full Length (1-214) |
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| RFL17143MF | Recombinant Full Length Mouse Membrane-Spanning 4-Domains Subfamily A Member 3(Ms4A3) Protein, His-Tagged | E.coli | Mus musculus | His | Full L. Full Length (1-213) |
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Involved Pathway
MS4A3 involved in several pathways and played different roles in them. We selected most pathways MS4A3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with MS4A3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
MS4A3 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MS4A3 itself. We selected most functions MS4A3 had, and list some proteins which have the same functions with MS4A3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | RBM5,ITGB1BP1,ACYP2,TDG,HMGA1,COMMD1,AKT1S1,RBM26,BLOC1S3,RTN4RL1 |
Interacting Protein
MS4A3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MS4A3 here. Most of them are supplied by our site. Hope this information will be useful for your research of MS4A3.
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References
- Eiring, AM; Agarwal, A; et al. The Tumor Suppressors, MS4A3 and G0S2, Are Downregulated in CML Cells with BCR-ABL1 Kinase-Independent Resistance. BLOOD 124:-(2014).
- Ishibashi, T; Yokota, T; et al. MS4A3 Marks Early Myeloid Differentiation in Human Hematopoiesis. BLOOD 124:-(2014).
