MS4A2
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Official Full Name
membrane-spanning 4-domains, subfamily A, member 2 -
Overview
IgE is the seventh immunoglobulin made by B cells in the immune response. -
Synonyms
MS4A2;membrane-spanning 4-domains, subfamily A, member 2;APY, FCER1B, IgE responsiveness (atopic) , IGER, membrane spanning 4 domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for;beta polypeptide);high affinity immunoglo
Recombinant Proteins
- Rat
- Human
- Mus musculus
- Mammalian Cells
- HEK293
- Human Cells
- Wheat Germ
- In Vitro Cell Free System
- E.coli
- His
- Non
- Flag
- Avi&Fc&His
- GST
Involved Pathway
MS4A2 involved in several pathways and played different roles in them. We selected most pathways MS4A2 participated on our site, such as Sphingolipid signaling pathway,Phospholipase D signaling pathway,Fc epsilon RI signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with MS4A2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Phospholipase D signaling pathway | PTPN11,AVPR2,PLA2G4A,INS2,PIK3R5,INS,PTK2B,CYTH2,SHC2,DGKE |
| Asthma | HLA-DOA,HLA-DMA,HLA-DRB3,PRG2,HLA-DMB,H2-AA,IL13,RNASE3,HLA-DQA2,IL9 |
| Fc epsilon RI signaling pathway | PIK3CG,FCER1G,MAP2K1,FCER1A,PLA2G4C,MAPK10,PIK3CA,MAP2K4,PIK3R3,PLCG1 |
| Sphingolipid signaling pathway | DEGS1,GNAI1,SGPP1,MAPK12,ASAH2,AKT1,PPP2R2A,GNAQ,MAPK13,MAPK8 |
Protein Function
MS4A2 has several biochemical functions, for example, IgE binding,IgE receptor activity,SH2 domain binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MS4A2 itself. We selected most functions MS4A2 had, and list some proteins which have the same functions with MS4A2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| SH2 domain binding | PTK2,LAX1,SRC,SHCBP1,INPPL1,GNB2L1,IRS1,PAG1,NUP62,SIT1 |
| phosphoprotein binding | PAFAH1B1,LRP11,IGF2R,FKBP4,DPYSL3,MID1,TBL2,YWHAE,RB1,SERPINB1A |
| IgE receptor activity | FCER1A,CD247L,FCER1G |
| protein kinase binding | SFN,PDGFRB,FAM83D,PPME1,SPDYA,SHC4,SMAD3,PRKAG3,DLG1,IKBKB |
| IgE binding | FCER2,Fcer2a,FCER1A,LGALS3,CD247L,FCER1G |
Interacting Protein
MS4A2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MS4A2 here. Most of them are supplied by our site. Hope this information will be useful for your research of MS4A2.
Resources
Research Area
Fc ReceptorsITIM/ITAM Immunoreceptors and Related Molecules
Granulocyte Markers
CD Antigen (Granulocyte Markers)
Macrophage Markers
Monocyte Markers
Dendritic Cell Pathogen Recognition/Uptake
Related Services
Related Products
References
