MRPS17
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Official Full Name
mitochondrial ribosomal protein S17 -
Overview
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S17P family. The encoded protein is moderately conserved between human mitochondrial and prokaryotic ribosomal proteins. Pseudogenes corresponding to this gene are found on chromosomes 1p, 3p, 6q, 14p, 18q, and Xq. -
Synonyms
MRPS17;mitochondrial ribosomal protein S17;28S ribosomal protein S17, mitochondrial;28S ribosomal protein S17;mitochondrial;HSPC011;MRP S17;RPMS17;OTTHUMP00000209315;OTTMUSP00000034586;OTTMUSP00000034588;OTTMUSP00000034590;OTTMUSP00000034591;OTTMUSP00000034592;1810006P02Rik;OTTMUSP00000034583;OTTMUSP00000034585;S17mt;MRP-S17
Recombinant Proteins
- Human
- Mouse
- Rhesus macaque
- Chicken
- E.coli
- Mammalian Cell
- HEK293
- HEK293T
- Wheat Germ
- In Vitro Cell Free System
- His
- Myc&DDK
- His&Fc&Avi
- GST
Involved Pathway
MRPS17 involved in several pathways and played different roles in them. We selected most pathways MRPS17 participated on our site, such as Ribosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with MRPS17 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Ribosome | MRPL23,RPL5B,RPL32,MRPL33,MRPS11,RPL13A,RPS6,RPLP1,FAUA,RPL7A |
Protein Function
MRPS17 has several biochemical functions, for example, rRNA binding,structural constituent of ribosome. Some of the functions are cooperated with other proteins, some of the functions could acted by MRPS17 itself. We selected most functions MRPS17 had, and list some proteins which have the same functions with MRPS17. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| structural constituent of ribosome | MRPL15,RPL3,UBA52,MRPL18,RPS23,RPS19,RPL5B,SLC25A15A,RPL18,RPS27L |
| rRNA binding | PTCD3,RPS4Y1,RPL23A,ANG,RPS9,KDM2B,NOL12,MRPL20,MTERFD2,RPS18 |
Interacting Protein
MRPS17 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MRPS17 here. Most of them are supplied by our site. Hope this information will be useful for your research of MRPS17.
PINX1;ssrna_ug;ESR1;ERBB3;ICT1;ECSIT
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