MRPS11
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Official Full Name
mitochondrial ribosomal protein S11 -
Overview
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that contains a high level of sequence similarity with ribosomal protein S11P family members. A pseudogene corresponding to this gene is found on chromosome 20. Sequence analysis identified two transcript variants that encode different protein isoforms. -
Synonyms
MRPS11;mitochondrial ribosomal protein S11;28S ribosomal protein S11, mitochondrial;cervical cancer proto oncogene 2;FLJ22512;FLJ23406;HCC 2;mitochondrial;28S ribosomal protein S11;28S ribosomal protein S11, mitochondrial precursor;Cervical cancer proto oncogene 2 protein;Cervical cancer proto-oncogene 2 protein;HCC-2;MRP S11;MRP-S11;RPMS11;RT11_HUMAN;S11mt
Recombinant Proteins
- Chicken
- Human
- Rhesus macaque
- Zebrafish
- Mouse
- Mammalian Cells
- E.coli
- HEK293
- Wheat Germ
- In Vitro Cell Free System
- His
- Non
- His&Fc&Avi
- Myc&DDK
- GST
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| MRPS11-1261C | Recombinant Chicken MRPS11 | Mammalian Cells | Chicken | His |
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| MRPS11-28172TH | Recombinant Human MRPS11, His-tagged | E.coli | Human | His | Full L. 1-194 a.a. |
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| MRPS11-2854R | Recombinant Rhesus monkey MRPS11 Protein, His-tagged | Mammalian Cells | Rhesus macaque | His |
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| MRPS11-3936Z | Recombinant Zebrafish MRPS11 | Mammalian Cells | Zebrafish | His |
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| MRPS11-4153HCL | Recombinant Human MRPS11 293 Cell Lysate | HEK293 | Human | Non |
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| MRPS11-2674R | Recombinant Rhesus Macaque MRPS11 Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| MRPS11-2674R-B | Recombinant Rhesus Macaque MRPS11 Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| Mrps11-4164M | Recombinant Mouse Mrps11 Protein, Myc/DDK-tagged | HEK293 | Mouse | Myc&DDK |
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| MRPS11-5600H | Recombinant Human MRPS11 Protein, GST-tagged | Wheat Germ | Human | GST |
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| MRPS11-6455HF | Recombinant Full Length Human MRPS11 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 194 amino acids |
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Involved Pathway
MRPS11 involved in several pathways and played different roles in them. We selected most pathways MRPS11 participated on our site, such as Ribosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with MRPS11 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Ribosome | MRPS6,MRPL33,MRPL15,RPS11,RPS13,MRPL18,RPS26,FAU,RPL23,MRPS14 |
Protein Function
MRPS11 has several biochemical functions, for example, mRNA 5-UTR binding,poly(A) RNA binding,small ribosomal subunit rRNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MRPS11 itself. We selected most functions MRPS11 had, and list some proteins which have the same functions with MRPS11. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| mRNA 5-UTR binding | RPS14,LARP1,DDX3X,IGF2BP3,IGF2BP2,IGF2BP1 |
| small ribosomal subunit rRNA binding | RPS14,RPS13,UTP23,CIRBP,RPS3,NSUN4,MRPS6 |
| poly(A) RNA binding | ISG20L2,RAN,Api5,ABT1,SARS2,ZFP598,SRSF9,WDR46,RPL5,ENO1 |
| structural constituent of ribosome | MRPS18B,SLC25A24L,MRPS17,RPS26L,RPS17,RPL18,NDUFA7,RPL5,MRPS22,MRPL19 |
Interacting Protein
MRPS11 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MRPS11 here. Most of them are supplied by our site. Hope this information will be useful for your research of MRPS11.
SRPK2;SRPK1;ssdna_dtdc;ICT1;SLX4;MAP1LC3A
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References
- Zikova, A; Panigrahi, AK; et al. Trypanosoma brucei mitochondrial ribosomes. MOLECULAR & CELLULAR PROTEOMICS 7:1286-1296(2008).
- Choi, SJ; Park, EJ; et al. Inheritance pattern of chloroplast and mitochondrial genomes in artificial hybrids of Porphyra yezoensis (Rhodophyta). FISHERIES SCIENCE 74:822-829(2008).
